The Football Association has confirmed that England will play Scotland in an international friendly at Celtic Park on Nov. 18.
The match signals England's first match north of the border since defeating the Scots in the Euro 2000 qualifying play-off 15 years ago.
Gordon Strachan's team lined up against England in a friendly international in August last year, where former Southampton striker Rickie Lambert scored the winning goal in a 3-2 victory for Roy Hodgson's side.
Now the Scottish Football Association and its counterparts at Wembley have agreed on a return fixture this year.
The forthcoming game will be played at Celtic Park rather than Hampden Park. This is because the national stadium will be undergoing refurbishment following its role in the Commonwealth Games this summer, where it has been converted into a venue for the athletics.
The England vs. Scotland fixture is the oldest in international football, with its debut appearance coming in 1872.
The game was an annual part of the domestic calendar in Great Britain as part of the Home International series, which also featured Wales and Northern Ireland in a four-team tournament at the end of the club season. However, the competition was abolished in 1984 as attendances for matches began to fall.
But the England vs. Scotland fixture continued as an annual match until 1989 under the guise of the Rous Cup.
Former Manchester United midfielder Paul Scholes scored twice on the last occasion England played in Scotland when Kevin Keegan guided his team to a 2-0 win at Hampden in the Euro 2000 play-off first leg.
Don Hutchison scored the only goal of the game in the second leg at Wembley, but it was not enough to see Craig Brown's team into the finals ahead of the Auld Enemy.