Reigning champions Spain take on the Netherlands in Day 2's headline game in the 2014 World Cup, a repeat of 2010's final in which La Roja prevailed.
Friday is the first full day of fixtures in Brazil, with three matches taking place across the country.
Mexico's clash with Cameroon and Chile's matchup with Australia complete the day's schedule as Group A and Group B get their opening matches over and done with.
There are plenty of opportunities for the punters during Day 2. Let's take a look at the latest betting lines.
Here are a few predictions ahead of the Friday's action.
Spain Will Have Enough For Dutch Test
In 2010, Spain lost their opening group game, going down 1-0 to Switzerland in a shock result. Vicente del Bosque's side are unlikely to repeat the trick on Friday in Salvador, despite the tough Dutch opposition who will be looking for revenge for South Africa.
What will be the result between Spain and the Netherlands?
The holders have enormous quality throughout their side, with the likes of Iker Casillas, Sergio Ramos and Gerard Pique at the back, and Andres Iniesta, Cesc Fabregas and David Silva further forward.
The returning Diego Costa also offers them a genuine striking option at the head of their devastating attack line, something they have lacked in recent times.
They are the top-ranked side in the world for a reason and they know how to win. They have the chance to make it four major-tournament wins in a row which should provide more than enough inspiration.
Spain will likely concede at least one goal against Louis van Gaal's Netherlands side as Robin van Persie's quality is proven by his international scoring record.
8 - Robin van Persie has scored eight goals in his last eight games for the Netherlands. Class.— OptaJohan (@OptaJohan) June 12, 2014
However, Spain should have enough to outscore their opponents and get this campaign off to a winning start.
Prediction: Spain 2-1 Netherlands
Chile and Mexico Should Start Strongly
Mexico only scraped into the competition in Brazil, forced into a playoff with New Zealand after a torrid campaign.
However, coach Miguel Herrera looks to have turned things around and he certainly seems confident ahead of the Cameroon clash, per beIN Sports:
Miguel Herrera speaking in press conference, ahead of Mexico game v Cameroon: "We can win the World Cup."— beIN SPORTS (@beINSPORTSUSA) June 12, 2014
El Tri sit 36 places above Cameroon in the world rankings, per FIFA, and they should make their quality show with a win over the African side.
Herrera named his team for the clash on Thursday, the most significant omission from the starting lineup being Manchester United's Javier Hernandez.
Manchester United striker Javier Hernandez has been left out of Mexico’s starting XI for their opening #WorldCup game against Cameroon— SuperSport Blitz (@SuperSportBlitz) June 12, 2014
While Australia will be eager to get off to a decent start in a very tough Group B, Chile's quality should shine through.
Chile have lost only three times in 18 games and they have never in their history lost to Australia, per David Brown in The Independent.
Alexis Sanchez, Eduardo Vargas and Arturo Vidal are the core of a very exciting Chile team and they will be eager to start with a win considering Spain and the Netherlands are their next fixtures. And it should be an easy win for Jorge Sampaoli's side in Cuiaba.
Prediction: Mexico 3-1 Cameroon, Chile 3-0 Australia