The loss of Argentina's main man would without doubt be a colossal blow to the team's chances of claiming glory in Brazil, but that does not mean Sabella shouldn't have a back-up plan just in case the unthinkable actually happens.
This outfit is entirely built around Lionel Messi and relies heavily on his creative spark and his goals.
It is rare for Messi to be withdrawn in any match, for either Argentina or Barcelona, but it would not be a bad idea for Sabella to give the team a 45-minute spell without the No. 10 in order to see how they adapt.
One option could be to replace him directly in the front three with a player like Ezequiel Lavezzi, who offers some of the attributes that Messi does, but obviously not all of them.
Another setup the coach could try would be to switch to a 4-4-2, push Angel di Maria further left and bring in another skilful wide player—such as Enzo Perez, Augusto Fernandez or Ricky Alvarez—to patrol the other flank and attempt to create chances for Sergio Aguero and Gonzalo Higuain up front.