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Miguel Layun (LB): The Cliub America defender will take over the left flank as he has done since Miguel Herrera took over the squad.
The Club America defender has already proven to be very flexible, as he can take over any of the flanks with the same productivity and technique.
Carlos Salcido (CB): He is one of the biggest surprises on the squad, but his experience will come in handy when the team plays in Brazil.
His natural position is on the left flank but since Marquez and Moreno will sit on the bench for this game, the Chivas footballer will help Reyes and Rodriguez inside the box.
Herrera can also use him as a left-back or a defensive midfielder, like he did at the 2012 Summer Olympics, since an ankle injury sidelined Juan Carlos Medina from the squad. Herrera will have at least four games to make up his mind about that issue.
This is a key game for Salcido, if he is out of shape, he can kiss goodbye his chance to be a starter in the upcoming games.
Francisco Rodriguez (CB): He has struggled a lot with his physical form, and he needs to work hard if he wants to leave the bench once in Brazil.
Since Hector Moreno and Rafael Marquez will not play in this game, El Maza needs to take it as an advantage and prove that he is ready to be back on the pitch. If he manages to prove he is in shape, Diego Reyes' spot could be in danger.
Diego Reyes (CB): One of the most trusted men of Miguel Herrera. Reyes may not be an undisputed starter with Porto, but he earned El Piojo's confidence when they were both part of Club America.
Reyes was a key footballer at the 2012 Summer Olympics, but he has yet to prove himself with the senior team. He has heart and gives it all on the pitch, but his lack of playing time could hurt his chances of making the starting XI.
His most valuable asset is his aerial game and he can thank his height (6'4'') for that.
Paul Aguilar (RB): He is one of the players who have no competition. Aguilar knows how to take care of the right flank like few players.
He is fast and ferocious, but furthermore, he has the ability to join the attack as a flying full-back, which is why he adjusts so well in Herrera's 5-3-2 system.
Aguilar has scored three times with El Tri, thanks to his powerful long-distance shot.