If they have learned anything from La Liga this season, Real Madrid will know that they should not relent in the title race.
On paper things look bleak for Los Blancos, especially after Cristiano Ronaldo, Pepe and Angel Di Maria were injured in their draw with Valladolid on Wednesday night.
It was a game that Real Madrid had to win to maintain a good chance of winning the league.
After they stumbled against Valencia on Sunday, barely managing to scrape a 2-2 draw, Carlo Ancelotti and his men knew that although the trip to the Estadio Nuevo Jose Zorrilla would be testing, they needed to win.
However, after just eight minutes, Ronaldo left the field injured.
Madrid director Miguel Pardeza said that the player had a sore calf and added that it didn't seem serious, as per AS.
He was substituted because of a left hamstring problem and Alvaro Morata took his place.
The same Spanish news site believes that Pepe and Di Maria's injuries are far more serious than Ronaldo's.
AS say that Pepe had a sharp pain in his calf and Di Maria felt discomfort with his hip and also had a groin injury, possibly a tear.
Having played so well this season it will be a huge blow both for the club and the player if he misses the Champions League final against city rivals Atletico Madrid.
Worse still for Di Maria, he fears he may miss the World Cup if he has suffered a groin tear.
With those three players potentially missing for the remaining two games of their league campaign, Madrid will find it tough going.
They next travel to Celta Vigo, to face Luis Enrique's side.
The former Barcelona star will want his team to make things tough for Real Madrid, particularly as Blaugrana supporters will be keeping a close eye on the game.
There has been much speculation that Enrique will be the next Barcelona manager and so troubling Madrid would be a good way to win over any unconvinced supporters.
If Madrid win both of those games, they will be on 90 points.
They would need Atletico Madrid to only pick up one more point in their two games and Barcelona could gain a maximum of four, if they are to win La Liga.
With Barcelona and Atletico facing each other in the final game of the season, it is possible.
Essentially, Real Madrid would need Atletico to lose to Malaga at home and then share the spoils with Barcelona on the final day of the season.
All three teams kick off at the same time on Sunday, 6 p.m. UK time.
Madrid need to go into their match against Celta Vigo with determination and focus.
Atletico were stunned by Levante last weekend and although they are expected to beat Malaga, it is possible they will falter again.
It has been a long season for Diego Simeone's side, who have played in almost every match possible for them.
Barcelona, meanwhile, travel to Elche.
Tata Martino's side have found things hard this season and Elche can be a tough side to break down.
The odds suggest Real Madrid are in a bad position, but if the last few weeks are anything to go by, victory is far from impossible.
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