Although clubs will always do everything they can within their means to prepare themselves for a difficult season, injuries are always a roll of the dice that are beyond the control of any board of directors.
This season, several Bundesliga clubs have been blighted by injuries. Borussia Dortmund are without doubt the most notable, their having to call Manuel Friedrich out of retirement and convert players to new positions being prime examples of the desperate situation they've faced.
But BVB are not the only club to have had injury problems. Schalke dealt without Klaas-Jan Huntelaar for long periods of time and cruciate ligament tears to Marco Hoger and Dennis Aogo left them extremely short of staff in defensive midfield.
Even Bayern Munich, the deepest club in the Bundesliga, have had injury problems, and a lack of fitness among key players has contributed to Hamburg's relegation fight.
Out of all the many injured players to miss out on time, B/R has identified the 10 most influential absences arranged alphabetically by surname. Click "Begin Slideshow" to see who makes the cut.