After the tedious Round One in Camp Nou, which included a waste of a punch by United (Cristiano Ronaldo's early missed penalty) and several testing forays by Barcelona (their few chances), all's set up for an exciting Round Two at Old Trafford after a blank score.
But Manchester United have sustained some blood wounds between the rounds. The possible injuries to Wayne Rooney and Nemanja Vidic after Saturday's loss to Chelsea. However, their strength is still not impaired. With armoury such as Cristiano Ronaldo, Carlos Tevez and Luiz Nani still left in the tank, they are still the slight favourites for the tie against the Catalan giants.
Here are the line-ups for the big game:
Manchester United (4-5-1): Van der Sar - Hargreaves, Brown, Ferdinand, Evra - Ronaldo, Park, Carrick, Scholes, Nani - Tevez
Barcelona (possibly 4-4-1-1 or 4-5-1: Valdes - Zambrotta, Milito, Puyol, Abidal - Xavi, Iniesta, Toure, Deco - Messi - Eto'o
Looking at the line-ups, Barcelona look menacing, with the possible attacking trio of Messi, Deco and Eto'o, and the bombing full-backs Zambrotta and Abidal. But United have threats of their own. Park's always reliable, Hargreaves slots in easily at right-back, and even without Rooney their attack looks formidible with the likes of Ronaldo, Scholes, Tevez and Nani.
Promises to be a cracking game, lots of goals. But if I was going for a score, I would say Manchester United to win 3-2.