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Bleacher Report's Dan Pompei reported that the Bills could be interested in trading with Houston for the first overall pick. He wrote in the article:
Word from the NFL meetings is the Texans are trying hard to deal the first pick in the draft. They want to move down and acquire extra selections. Sources say they might have a trade partner in the Bills, who appear interested in moving up.
It would not surprise me if the Bills had contacted the Texans about the first overall pick, most likely for the opportunity to draft Jadeveon Clowney. There are two major roadblocks that would hinder a potential trade between the Texans and the Bills.
The first is that the Bills would have to give up numerous draft picks to move up that high and that doesn't fit GM Doug Whaley's philosophy. He has made it clear that he wants to build this team through the draft, so to trade away the amount of picks necessary to move up would be surprising.
The other potential hurdle in this trade is the fact that while the Texans probably do want to trade back and acquire extra picks, they probably don't want to trade all the way back to the ninth spot. By moving that far back in the draft, they would run the risk of missing out on one of the top quarterbacks in this year's draft.