The most one-sided of all the quarter-final ties on paper appears to be Bayern Munich v Manchester United.
The Bavarians, who won this competition last year, have already romped to the German title and can now focus their full attention on the Champions League.
United, meanwhile, are enduring a horror season after the departure of Sir Alex Ferguson, having slumped to seventh in the league.
The task of overcoming Pep Guardiola's wonderful side is likely to be too much for David Moyes' side to achieve, but it could well offer up more of a fight, in the first leg at Old Trafford especially, than many expect.
Bayern have lost one of their midfield hubs in Thiago Alcantara to injury and central defender Dante to suspension.
Though they were able to rest players in the Bundesliga on the weekend, such a tactic can sometimes result in the loss of rhythm when the side is reassembled at full strength.
There is also the risk of complacency in the German squad, though Guardiola will no doubt be trying to eradicate any such sentiments, if they exist.
Ian Herbert of The Independent gave an indication of how confident German pundits are ahead of the clash with this tweet:
The Red Devils may offer up a bit more of a scrap than many anticipate.