It's first against third this weekend as Chelsea take on Arsenal at Stamford Bridge, with the hosts looking to react in the title race after their 1-0 defeat at Aston Villa.
The Gunners will be looking to build from their 1-0 win at fierce rivals Tottenham, while second-placed Liverpool are also buzzing after a big win as they travel to struggling Cardiff.
Norwich face Sunderland in a scrap of the bottom six, with both needing a win to aid their chances of escaping the drop zone.
Here are predictions for all of Week 31's games, which also include a bunch of midweek fixtures:
|EPL Week 31: Fixtures, TV Info, Live Stream and Predictions|
|Date||Time||Fixture||TV Info||Live Stream||Prediction|
|March 22||12.45 p.m. GMT, 8.45 a.m. ET||Chelsea vs. Arsenal||BT Sport||BT Sport app||2-1|
|March 22||3 p.m. GMT, 11 a.m. ET||Cardiff vs. Liverpool||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||1-3|
|March 22||3 p.m. GMT, 11 a.m. ET||Everton vs. Swansea||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||2-0|
|March 22||3 p.m. GMT, 11 a.m. ET||Hull vs. West Brom||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||1-2|
|March 22||3 p.m. GMT, 11 a.m. ET||Man City vs. Fulham||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||4-1|
|March 22||3 p.m. GMT, 11 a.m. ET||Newcastle vs. Crystal Palace||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||1-1|
|March 22||3 p.m. GMT, 11 a.m. ET||Norwich vs. Sunderland||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||0-2|
|March 22||3 p.m. GMT, 11 a.m. ET||West Ham vs. Man Utd||Sky Sports||Sky Sports app||1-0|
|March 23||1.30 p.m. GMT, 9.30 a.m. ET||Tottenham vs. Southampton||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||3-1|
|March 23||4 p.m. GMT, 12 p.m. ET||Aston Villa vs. Stoke||NBC Sport Live Extra (US Only)||NBC Sport Live Extra app||2-2|
|March 25||7.45 p.m. GMT, 3.45 p.m. ET||Arsenal vs. Swansea||TBC||TBC||2-0|
|March 25||7.45 p.m. GMT, 3.45 p.m. ET||Man Utd vs. Man City||Sky Sports||Sky Sports app||2-2|
|March 25||7.45 p.m. GMT, 3.45 p.m. ET||Newcastle vs. Everton||TBC||TBC||1-3|
|March 26||7.45 p.m. GMT, 3.45 p.m. ET||West Ham vs. Hull||TBC||TBC||2-0|
|March 26||8 p.m. GMT, 4 p.m. ET||Liverpool vs. Sunderland||Sky Sports||Sky Sports app||4-2|
Chelsea vs. Arsenal
Jose Mourinho's men go into their bout with Arsenal on the back of a 2-0 win against Galatasaray in the Champions League.
Sitting four points behind the Blues with a game in hand, Arsenal know their hopes of clinching their first title in 10 years would receive a huge boost with victory at the Bridge.
But to do that, they will have to beat a Chelsea side who are unbeaten in 75 home league matches under Mourinho, as tweeted by FootballFanCast:
The Blues' performance against Villa highlighted the side's vulnerability when put under serious pressure, which saw them buckle in the Midlands.
Ramires and Willian were both sent off for the visitors, so they will be unavailable for the visit of Arsene Wenger's men.
This will force a reshuffle and may see a return for David Luiz in the Blues' customary midfield five.
It'll be the high tempo executed by Villa that Arsenal will have to replicate if they are to end Mourinho's excellent home record.
Prediction: Chelsea 2-1 Arsenal
Cardiff vs. Liverpool
These two sides meet at the Cardiff City Stadium chasing survival and the title, respectively.
Liverpool's 3-0 win at Manchester United last time out showed that Brendan Rodgers' men are up for the challenge of winning their first Premier League trophy.
But they come up against a Welsh outfit looking for revenge against Merseyside opposition, after succumbing to a last-minute defeat at Everton in Week 30.
Cardiff went into their match with the Toffees looking to make it two wins in a row, and after Juan Torres Ruiz cancelled out Gerard Deulofeu's opener, a share of the spoils looked likely.
However, Seamus Coleman had other ideas as he netted with minutes to go to condemn Cardiff to their 17th defeat of the season.
Speaking after his team's win, Roberto Martinez told BBC Sport of his belief that Cardiff will survive the drop this season:
Looking at [the] performance I think Cardiff will have enough points to achieve their aim. It's fair to say that Cardiff were magnificent in what they did. think they were very aggressive in the right manner. There was a real good intensity with what they were doing.
They were flexible tactically. They started with a back three. They swapped it around and they adapted really well. Ole Gunnar Solskjaer has brought a different approach in the way they play. I think they've got something really strong going.
Cardiff are capable of giant-killing acts. Their 3-2 home victory against Manchester City and 2-2 draw with Manchester United should serve as a warning to Liverpool.
The Bluebirds also managed a goal at Anfield, although Liverpool won the reverse fixture 3-1. Luis Suarez—who netted a brace and created Raheem Sterling's strike—proved too hot to handle on the day.
It'll be up to the Reds' attacking trio of Suarez, Sterling and Daniel Sturridge to bag the goals once again, with a combined 49 league strikes between them this season, per WhoScored.com.
Going into the game on the back of an Old Trafford win will boost the title chasers, and with 52 goals conceded already this season, it could be damage limitation in Wales.
Prediction: Cardiff 1-3 Liverpool
Norwich vs. Sunderland
Sunderland go into their second bottom-six clash in as many weeks as they travel to Carrow Road to face Norwich.
The hosts sit in 15th place and hold a five-point lead over 18th-placed Black Cats, with Gus Poyet's men holding three games in hand.
Chris Hughton's outfit fell to a 4-2 defeat at Southampton last time out, despite pulling two late goals back to give themselves a chance at 3-2.
Johan Elmander's strike from the bench presented an interesting statistic, as tweeted by OptaJoe:
Sunderland's performance in the recent 0-0 draw against Crystal Palace will provide some confidence as they travel to East Anglia.
Per BBC Sport, the hosts held 65 percent of possession against Tony Pulis' outfit and had five shots on target, compared to Palace's two.
Poyet will have to make sure his side can make their chances count at Carrow Road, while Norwich look for their fourth home league shut-out in their last five matches, per WhoScored.
Prediction: Norwich 0-2 Sunderland
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