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No. 1 Arizona (30-4), No. 2 Wisconsin (26-7), No. 3 Creighton (26-7), No. 4 San Diego State (29-4)
Oklahoma State (21-12) was ranked in the Top 10 in early January before a major skid—compounded by Marcus Smart's suspension—sent the Cowboys into a tailspin. Nobody ever said the Cowboys weren't a good team, they just hit a wall in the middle of the season, leading to an eighth-place finish in the Big 12 and a No. 9 seed.
Make no mistake, OSU is the most dangerous team in an No. 8 vs. No. 9 game and could be Arizona's biggest hurdle to a Final Four appearance.
Sleeper to Watch
Oregon (23-9) lost five straight games after a 13-0 start, and everyone pretty much wrote off the Ducks. But then they rattled off seven in a row to end the regular season, including knocking off Arizona, showing off their flash-and-dash style that's high on energy, though it's low on defensive effort.
The Ducks are a poor-man's version of Iowa State, using the same style of play and featuring just as many impact transfers. The Ducks have the talent to make the Sweet 16 and shouldn't be ignored.
Why It's the Second-Weakest Region
If regions had a nickname, this would be the Chalk Region. That's because the top four seeds should all make the Sweet 16, and it has the best chance of drawing a No. 1 vs. No. 2 matchup in the regional final in Anaheim.
The one hiccup to that could be Creighton, which could ride the scoring stylings of Doug McDermott into the Elite Eight or beyond, much the way teams like Indiana State and Michigan State drafted behind superstars Larry Bird and Magic Johnson to the 1979 NCAA final.
Arizona has a relatively soft road to the Final Four, with its toughest matchup coming potentially in the third round. Distance can also play a factor in this region, with the Wildcats getting the chance to play the second weekend in one of its alumni hotbeds.
There's more potential for upsets here than in the East, but still not many. North Dakota State could be a trendy pick over Oklahoma, but after that it's a crapshoot.