There is little doubt where the biggest matches of the weekend lie this time around, with old rivals meeting on a huge Sunday in England.
Manchester United versus Liverpool is still one of the most anticipated fixtures worldwide, with this clash at Old Trafford seeing a role reversal from the usual as Brendan Rodgers' Reds arrive in Manchester still chasing the Premier League title.
David Moyes will be determined to stop them in their tracks and inject a little cheer into his side's season, whilst Sunday also sees a huge North London derby at White Hart Lane with major ramifications in both the title race and the battle to get into next season's Champions League.
Tottenham will be desperate to bounce back from their 4-0 loss at Chelsea last week, whilst Arsenal still have eyes on Premier League glory and will be smarting from their Champions League exit.
In Spain, Real Madrid could go six points clear at the top of La Liga for a couple of hours as they head to mid-table Malaga, but in truth all of the top three should earn victories this weekend as Atletico Madrid go to Espanyol and Barcelona host Osasuna on Sunday.
Serie A leaders Juventus are at Genoa on Sunday, where a win would take them a huge 17 points clear, ahead of Napoli's trip to Torino on Monday, when Roma also host Udinese.