Nemanja Vidic has already sealed his switch to Italy after failing to receive an extension to his current Old Trafford deal, and with the side languishing outside of Champions League football, Hernandez could yet leave the club.
The Mexican forward, known as Chicharito, has contributed two goals and two assists this season, largely being used as a substitute by manager David Moyes.
But with his future to think about and looking out of Moyes' long-term plans, the 25-year-old looks set for a move to the San Siro, according to Hopkinson:
Inter have spoken with the Mexican's father, who acts as his agent, and are now preparing to make contact with the Premier League side ahead of a formal offer of around £12 million. United will demand closer to the £15m mark and, if a deal can be struck, then Hernandez will be offered similar personal terms to those he is on at United of around £2 million a season.
Hernandez's contract is up in the summer of 2016 and United boss David Moyes has to decide whether or not to let the player leave as he begins his overhaul of the club. The striker, who is also coveted by Valencia, is down the pecking order when Moyes has a full complement of forwards to choose from.
Inter haven't won Serie A since 2011, and they have also failed to pick up any silverware in the last three years, making their need for a proven striker a priority to complement forwards Rodrigo Palacio, Mauro Icardi and Diego Milito.
The Italian club's owners, International Sports Capital, and president Erick Thohir will be looking to see their side return to winning ways after purchasing 70 percent of the club in October 2013.
However, with Hernandez linked with a summer switch, Sky Sports football writer Tom McDermott ponders the point on whether the striker would thrive at a lower-half Premier League club, let alone the Italian giants:
Speaking while on international duty, the forward showed his frustration as he fails to break into Moyes' starting side, according to Mirror's David McDonnell:
I'm very eager to play as my club don't take me much into account. I hope I have the opportunity to play [for Mexico]. When you are called up, you have to be thankful and if not called up, you have to keep working. I'm very happy and thankful with this call-up, like I was when I was called up for the first time.
Hernandez looks set to be one of a number of faces to be exiting Old Trafford this season and not just the only striker, as Telegraph's Mark Ogden believes that Robin van Persie could also be part of Moyes' summer exodus.
Moyes looks set to add a fresh face to his United side, masking this year's woes as he looks to build the club's long-term future, which could see many Old Trafford favourites leave.
But could offloading the Mexican prove to the club's detriment, as a pacy forward with a poaching instinct?
The striker has scored 35 goals in 93 league appearances since joining the club in 2010—a strike rate of better than one in three—while hitting seven goals in 22 Champions League appearances for the Red Devils.
Finding a striker with such natural ability as Hernandez will be difficult, too, with the striker's proven talents of popping up at vital moments to score important goals. This was shown by his two goals as United progressed to the Champions League quarter-finals after a 2-1 home win against Marseille in 2011:
Should the club offload Hernandez and with van Persie's future unclear, the club would be left with just England pair Wayne Rooney and Danny Welbeck, with an injury to either forward leading to a selection headache and probable formation change for Moyes.
With little time to prove his worth on the pitch, too, Hernandez's frustrations will no doubt be felt by the United supporters, who will know just how important the player can be to their side.
It's not just good feet that help Hernandez's forward play, though; it's his ability to pick the perfect place to run into when bearing down on goal and, more often than not, tucking home from close range.
But also his ability in the air makes him an excellent prospect for any side, with the striker's leap meaning that, even for a short forward, he has the ability to bag a few goals in the air.
Moyes' biggest mistake this summer may not be bringing in an ineffective marksman but letting an extraordinarily talented one leave without a real chance to prove his worth.
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