The Premier League calendar on Week 29 is beset by postponements owing to the FA Cup quarter-finals and the involvement of some EPL sides.
As such, only five fixtures will be played in England's top league over the coming weekend.
Jose Mourinho has never lost a league match at home with Chelsea, and he will be looking to extend that record to cement the Blues' place at the top of the table.
Here are the games for Week 29 and a closer look below at the biggest games of the weekend.
|Premier League: Week 29 Fixtures|
|Tottenham Hotspur vs. Chelsea||March 8||5.30 p.m. GMT/12.30 p.m. ET||1-2|
|West Brom vs. Manchester United||March 8||12.45 p.m. GMT/7.45 a.m. ET||2-1|
|Cardiff vs. Fulham||March 8||3 p.m. GMT/10 a.m. ET||1-3|
|Crystal Palace vs. Southampton||March 8||3 p.m. GMT/10 a.m. ET||1-1|
|Norwich City vs. Stoke City||March 8||3 p.m. GMT/10 a.m. ET||0-2|
Chelsea vs. Tottenham
Tim Sherwood takes his Spurs side to Stamford Bridge in the midst of his team's best form of the season.
Only two losses in the last 12, per WhoScored.com, will give the North Londoners confidence that they can end a 24-year hoodoo that hasn't seen a Lilywhites win in West London since Gary Lineker headed the winner back in 1990.
Just to put that in perspective, Gareth Bale was six months old.
Jose Mourinho has a record of his own to preserve. In two spells as manager at Chelsea, he has never lost a home league match.
In Emmanuel Adebayor, Tottenham possess one of the most in-form strikers around. Five goals in five games and a big physical presence will give both John Terry and Gary Cahill a difficult afternoon's work.
Chelsea have a cool customer of their own in Eden Hazard, and if he is allowed time and space, he is likely to continue Spurs' woes at the venue for another season.
A win would see Chelsea stretch their lead at the top to seven points with none of their nearest rivals in action this weekend.
Cardiff City vs. Fulham
To say this is a must-win game for both sides is to state the blindingly obvious.
Although Felix Magath's Fulham side find themselves propping up the rest of the table, the heat is probably more on his opposite number Ole Gunnar Solskjaer.
The Norwegian has overseen just one win since taking charge of the Bluebirds seven games ago, and his side have failed to score in five of those matches.
There could never be a better time for misfiring local hero Craig Bellamy to find his shooting boots.
The game is likely to be dictated in the midfield, and the matchup between "The Pitbull" Gary Medel and Fulham's Scott Parker could be explosive.
Medel perhaps needs to rediscover the fire that has made him such a fearsome competitor, one yellow card since the turn of the year indicative of a calmer and less effective player.
Magath is only interested in keeping Fulham in the league—at any cost. He has already dropped Lewis Hotlby from his squad, and as Jacob Murtagh of the Daily Mirror reports, he could be about to bring Mahamadou Diarra back into the fold.
Fulham fans worried about the drop should rest easy. According to Sami Mokbel of the Daily Mail, Jose Mourinho rates the German as one of the best managers in the league.
West Brom vs. Manchester United
David Moyes takes his struggling United side to the Hawthorns, a place where the Red Devils traditionally struggle.
Sir Alex Ferguson's final game as a manager turned into a 10-goal thriller here, but Moyes will surely be happy with a win by the odd goal.
With four goals in the last six, per WhoScored.com, his expected absence will be a huge blow.
Pepe Mel's West Brom have dropped like a stone to 17th in the table, and the Spaniard is desperate for a win to silence the critics who almost saw him out of a job.
Without a win since taking charge, "constructive" talks have already been held with the club's board, per BBC Sport.
Three home draws in the last four games, including holding Liverpool and Chelsea, have given fans hope that something can still be salvaged from the season.
The home side need to make full use of Thievy's lightning speed against a laboured United back line. The forward will score goals if given the right service and much will depend on the ability of Chris Brunt and Morgan Amalfitano to provide the same.