Roma vs. Inter isn't quite the top-of-the-table clash that it has been in recent seasons, but it's a fixture that's still vital to both clubs.
The Giallorossi can't afford to drop points if they want to maintain their slim chance of catching Juventus, while the Nerazzurri will want to make every game count if they're to stay in fifth, just ahead of this year's surprise package, Hellas Verona.
There's also the prospect that Fiorentina, ahead of Inter by five points, could drop points to Edy Reja's Lazio. And with Juve facing Clarence Seedorf's resurgent Milan at the San Siro, Roma could steal a march by winning, too.
With so much at stake, what will be the key battles to watch in this game?