In a word—no.
Adding another—no chance.
The Lakers sit 13th in the West heading into Tuesday night's action, nine-and-a-half games out of the final playoff spot and just a precarious half-game up from being in the Western Conference cellar.
Their offense has lost all its usual potency, ranking 22nd in the league in points per possession.
During Kobe Bryant's tenure in Los Angeles, the Lakers have never finished lower than 11th in that category.
Defensively it's even worse, as L.A. rates 26th in the NBA in points allowed per possession. That's not surprising given the roster composition and the way Mike D'Antoni likes to play.
No team has allowed their opponents to attempt more field goals in the restricted area than the Lakers. And it's not even that close. The Boston Celtics, who surrender the third most attempts at the hoop, are closer to 17th in that category than they are to the Lakers.
Corner-three-point attempts and field goals right at the rim are the two juiciest shots in basketball—the shots that every offense aims to generate on each possession—and the Lakers give up those prime looks more frequently than any other team in the league.
Bryant and Nash—two notably subpar defenders—won't help any in that department.
Where they can be of use, however, is on the offensive end.
The two haven't played a single minute together this season, but in 2013 the Lakers were vastly superior on offense when their two starting guards were on the court at the same time.
When both were off the court, the Lakers only mustered 101 points per 100 possessions—roughly equivalent to the 20th-ranked Celtics' output and almost identical to the rate they have scored at this season (per NBA Wowy).
So, theoretically, getting Bryant and Nash back in the lineup would instantly vault their offense into the league's upper echelon.
But let's not forget that both of these guys are coming off of serious injuries that have caused them to miss more time than they ever have in their careers. There's no guarantee they'll ever get back to the levels they were at even one year ago.
Oh, and they're both in their 18th season in the NBA and will be a combined 75 years old (!) after Nash turns 40 on Feb. 7.
We saw how rusty Bryant was in his first comeback earlier this season. It will take quite some time for them to get back into any sort of rhythm.
Time, though, is definitely not on L.A.'s side.
The projected win total of the current No. 8 seed in the West is 46. The Lakers would have to win 30 of their 37 remaining games just to match that.
And they would have to leapfrog five teams along the way.
Meanwhile, only four teams in the entire league have a worse nightly point differential than the Lakers—not a good sign for their future prospects.
Even when Bryant and Nash get back on the court, the rest of the conference is too stacked and the rest of the roster is too weak for the Lakers to even dream about a postseason berth.
So unless you define "making a run" as "playing .500 ball", the Lakers should set their sights not on the playoffs, but on the all-important draft lottery instead.
Note: All statistics as of January 26. Advanced statistics courtesy of NBA.com unless otherwise noted.