The Italian international has found his place come under siege this term, with Antonio Conte preferring his trio of Arturo Vidal, Andrea Pirlo and Paul Pogba.
The Express' Ben Jefferson has hinted that Juve's failure to progress into the Champions League knockout rounds could lead to a winter exit for the playmaker, writing:
Juventus were knocked out of the Champions League in December and reports suggested that Marchisio might be sacrificed to help offset the resulting financial shortfall, estimated at £17m.
Marchisio is reportedly surplus to requirements at Juve with Paul Pogba and Arturo Vidal considered the midfield of the future by the Italian club.
Jefferson goes on to say that a £20 million move for Marchisio's signature is obstructed by the player's wish to continue on at the club which he grew up in.
CNN's Tancredi Palmeri does say a move for Marchisio is plausible, though:
However, it could be a blessing in disguise for United if Marchisio does wish to remain at the Old Lady, considering David Moyes' club don't have the best track record when it comes to making long-term successes out of their Italian signings.
Among the players to have shown some promise but eventually amount to little at Old Trafford are Giuseppe Rossi, Federico Macheda, Massimo Taibi, Rodrigo Possebon and Carlo Sartori.
With that being said, Marchisio is an altogether more experienced asset than any Italian the club has had before, but the promise to turn the Red Devils' season around still isn't there.
Serie A's demands are far different to that of the Premier League in that the often languid approach is something of a far cry from the fast, relentless design of the English top flight.
To an extent, Marchisio thrives in the former. According to Squawka, the 27-year-old boasts a passing accuracy of 86 percent from his 14 appearances this term, just three percent less than that of the maestro Pirlo.
Considering his profile as a holding midfielder, the player's tackling success of less than 50 percent isn't entirely encouraging, nor is the fact that he's already given away 20 fouls this term.
That lack of physical dominance isn't what United need right now, and it's plausible that this aspect of Marchisio's game would only suffer further if he were to move to England, where a player's work rate off the ball is so critical.
Despite his drop in playing time this term, The Guardian's Paolo Bandini insists there's still a future in Turin for Marchisio:
That's not to say Italy isn't to be praised for the general understanding of tactical nuance that's on show with a lot of Serie A managers, but there's better ways that Moyes' millions can be spent as of this moment.
Europe has been the perfect arena to showcase this lack of physical understanding, where Juve have found themselves undone when coming up against the continent's big guns in the Champions League.
Vidal would be a better example of a player who has a better understanding of this facet of the Premier League's demands, but then, the Chilean has the advantage of being schooled differently from his days with Bayer Leverkusen.
Right now, United would be wise to concentrate their funds elsewhere, lest they find Marchisio following the example of Marouane Fellaini, falling short of the mark.