Rose was likely going to be the starter at the point guard position or perhaps battle it out with Kyrie Irving. However, after tearing his meniscus and being ruled out for the season, Rose's spot on the All-Star team is no longer a possibility despite being third in guard voting for the Eastern Conference.
The remaining three players all have legitimate shots.
Deng is a two-time All-Star, making the team the last two seasons. Noah joined his teammate for the first time ever in his career during the 2012-13 season after being voted in by the coaches.
Boozer's last All-Star appearance was in 2008 as a member of the Utah Jazz. Since then, his numbers have gone down, but he still remains a legitimate scoring 4 in the East.
The competition and star power in the East will make it hard for the Bulls to crack the starting lineup, but like the past two seasons, there's likelihood that they'll be selected as reserves by the coaches.
Chicago may be going through a tough year, but its presence during All-Star weekend could still be felt.
Season Averages: 14.9 PPG, 9.1 RPG
Boozer started off the year with some strong performances but over the last few weeks, his efficiency has drastically decreased. In eight of his last 11 games, Boozer has shot under 40 percent from the field, going as low as 22 percent during one contest.
The 12-year forward still has some bright spots, though. He's had eight double-doubles this year, tying him for 11th in the East. Last year he was second in the conference with 44.
There's a small chance Boozer is able to make a case. He'd have to turn his recent performances around and start posting elite power forward numbers this final month before balloting concludes on Jan. 20.
Even then, the competition at the frontcourt positions is tough, including his own two Bulls teammates who are outplaying him as of late.
Boozer will have to turn it on, but chances are he misses the cut once again.
Chance of making roster: 10 percent
Season Averages: 10.1 PPG, 9.4 RPG, 3.5 APG, 1.1 BPG
After suffering a groin injury during training camp, Noah had a slow start to the year as he fully recovered and got back into rhythm. During the month of December, Noah has averaged 12.5 points per game on 52-percent shooting, 11.6 rebounds and just under two blocks.
Noah leads the Bulls in frontcourt votes with 75,229, placing seventh among the vote-getters for that position.
Last year, the league changed the formation of the All-Star roster, removing the center position and making it two guard spots and three frontcourt spots.
The starting frontcourt spots are all but locked in, but Noah has a chance to earn another reserve spot.
Noah will need to maintain his double-double averages and top-level defensive play in order to beat out some of the other centers.
Chance of making roster: 35 percent
Season Averages: 19.6 PPG, 7.0 RPG, 4.1 APG
Since Rose's injury on Nov. 22, Deng has averaged 24 points per game on 50-percent shooting, six rebounds and five assists in nine games played. In comparison, LeBron James' season averages are 26 points, six assists and nearly seven boards.
Not to say Deng is as good as James, but Deng is proving he's still one of the best two-way small forwards not just in the East but in the NBA.
Deng has stepped up in the absence of the Bulls' superstar point guard and become Chicago's No. 1 offensive option. He's tailored his style of play to become more effective for the Bulls.
According to Synergy, Deng is used in post-up plays nearly 13 percent of the time, the second-highest rate excluding transition plays. He's shooting 51 percent on post plays and ranks 12th in points per play in that category with 1.04.
Defensively, he's as solid as always, holding opponents to 35-percent shooting and allowing .8 points per play.
Which Bulls players will make the All-Star team?
Players like Paul George, Carmelo Anthony and James will earn more votes than him, but coaches award Deng's style of play. Seeing as how he's taken on a bigger role this year, there's no reason he can't compete for another reserve spot.
Teams with losing records rarely have players selected to the All-Star team, but Chicago could even out by late January, and if Deng can stay healthy and maintain his numbers, his chances of making the team are pretty high.
Chance of making roster: 40 percent
It's looking like a rough year for Chicago, and its title hopes were essentially ended once Rose was lost for the season. With no consistent scoring options, the Bulls are relying on their defense to win every game.
It could be a long year for the Bulls as they try to stay alive in the East and figure out Deng's future with the team.
Still, if any bright spots come out of this year, it could be Deng making his third consecutive All-Star team while Noah makes his second in as many years.
Boozer may never get the chance to suit up in an Eastern Conference All-Star jersey, but Deng and Noah are playing at a high level and could get another reserve spot.
Note: All stats are accurate as of Dec. 19 before games were played.