Premier League Week 17 pits Arsenal against Chelsea, a clash that could see Jose Mourinho's team topple their London rivals from top spot.
Cardiff embark on a difficult journey to Liverpool, who also have the chance to go top of the table, while Manchester United host West Ham and Manchester City travel to Fulham.
Let's take a look at the full schedule, television information, live stream details and a full rundown of predictions before smashing through the most intriguing games to watch this weekend.
|Premier League Week 17 Schedule & Predictions|
|Liverpool vs. Cardiff||Dec. 21||12:45 p.m. GMT/7:45 a.m. ET||BT Sport||4-0|
|Crystal Palace vs. Newcastle||Dec. 21||3 p.m. GMT/10 a.m. ET||1-2|
|Fulham vs. Manchester City||Dec. 21||3 p.m. GMT/10 a.m. ET||1-3|
|Manchester United vs. West Ham||Dec. 21||3 p.m. GMT/10 a.m. ET||2-0|
|Stoke vs. Aston Villa||Dec. 21||3 p.m. GMT/10 a.m. ET||2-1|
|Sunderland vs. Norwich||Dec. 21||3 p.m. GMT/10 a.m. ET||1-1|
|West Brom vs. Hull||Dec. 21||3 p.m. GMT/10 a.m. ET||2-1|
|Southampton vs. Tottenham||Dec. 22||1:30 p.m. GMT/8:30 a.m. ET||Sky Sports||2-2|
|Swansea vs. Everton||Dec. 22||4 p.m. GMT/11 a.m. ET||Sky Sports||1-2|
|Arsenal vs. Chelsea||Dec. 23||8 p.m. GMT/1 p.m. ET||Sky Sports||2-1|
BT Sport subscribers can view Liverpool vs. Cardiff via the BT Sport app.
U.K. viewers can watch Sky Sports’ live games on the Sky Player website or via Sky Go for laptops and mobile devices (subscription required). Live scores are also provided on Sky Sports News throughout each match.
All highlights are available without the need for subscription on Match of the Day (BBC One, Saturday) or Match of the Day 2 (BBC2, Sunday). The latter programme can be found on BBC iPlayer from Monday.
Best Games to Watch This Weekend
Southampton vs. Tottenham
Southampton's excellent start to the season has vanished. Mauricio Pochettino's men have dropped to ninth after winning only one of their last six games and will be itching to claw back some points on those above them when Spurs visit St. Mary's.
Times are desperate for the visitors, who have installed Tim Sherwood as interim manager after the sacking of Andre Villas-Boas, per Martyn Ziegler of The Independent.
Sherwood will be looking to move Spurs away from the cautious, laborious football played under their former boss and may opt to utilise two strikers in a bid to improve on their poor average of 0.94 goals per game this Premier League season, reported by WhoScored.com.
OptaJoe's prominent stat after the 5-0 defeat to Liverpool also heightened the sense of panic around the Spurs camp:
Both teams need a win to turn their season around. Expect attacking football, plenty of chances and potentially a Spurs outfit that plays nothing like the hapless style shown against Brendan Rodgers' side.
Swansea vs. Everton
It's remarkable to consider Everton have only suffered one loss this deep into the season. Roberto Martinez and his players are excelling themselves against the best, but the trip to Swansea will examine the squad once more.
The Swans have lost just one of their last six and are proving difficult to beat, even with terrible injury problems.
Michael Laudrup's side can overcome anyone on their day, but their trademark short-passing game will need to be sharp if they are to bypass an Everton team that continually squeezes their opponents out of possession.
This game is likely to come down to which side takes their chances. Should Everton escape the Liberty Stadium with three points in the bag, it might be time seriously to consider the Merseyside club for a spot in next season's Champions League.
Arsenal vs. Chelsea
Arsenal's 6-3 loss to Manchester City puts extra pressure on Arsene Wenger's side heading into this match, but if they are to win the Premier League, this is exactly the test from which they need to gain three points.
The Gunners' only home loss of the season came in the opening-day defeat to Aston Villa, while Chelsea have suffered three losses on the road this campaign, not including the recent Capital One Cup quarter-final failure against Sunderland.
To make things even tastier, Chelsea knocked Arsenal out of the aforementioned tournament with a 2-0 win at the Emirates in October.
Wenger's side need to keep the ball more effectively than the last encounter and may call on the pace of Theo Walcott to aid a rapidly tiring Olivier Giroud up top.
Walcott highlighted his finishing skills with a brace against City and has the incisiveness to stretch a Chelsea defence that has conceded eight across their last three Premier League matches.