NFL Picks Week 15: Latest Spread Info and Upset Predictions

R. Cory SmithSenior Writer IDecember 13, 2013

NEW ORLEANS, LA - SEPTEMBER 30:  Quarterback Ryan Tannehill #17 of the Miami Dolphins celebrates after running back Lamar Miller #26 scores on a five-yard touchdown run in the second quarter against the New Orleans Saints at the Mercedes-Benz Superdome on September 30, 2013 in New Orleans, Louisiana.  (Photo by Chris Graythen/Getty Images)
Chris Graythen/Getty Images

Week 15 in the NFL doesn't offer a ton of exciting matchups outside of the prime-time games, but there are certainly quite a few games that could see the underdog make the game close or even pull off a win.

With just three weeks remaining in the regular season, bettors are looking to line their pockets with huge upsets before the playoffs begin. While some games might not be the best for the eyes, here are the games where the underdog will pull off the upset.

Complete Week 15 Predictions
AwayHomeSpreadPick ATS
San Diego ChargersDenver BroncosDEN -10.5Chargers
Buffalo BillsJacksonville JaguarsBUF -2Jaguars
Chicago BearsCleveland BrownsCLE -2Bears
Houston TexansIndianapolis ColtsIND -6Colts
New England PatriotsMiami DolphinsNE -2.5Dolphins
Philadelphia EaglesMinnesota VikingsPHI -4.5Eagles
Seattle SeahawksNew York GiantsSEA -7Seahawks
San Francisco 49ersTampa Bay BuccaneersSF -5.549ers
Washington RedskinsAtlanta FalconsATL -6Falcons
New York JetsCarolina PanthersCAR -11Panthers
Kansas City ChiefsOakland RaidersKC -4Chiefs
Green Bay PackersDallas CowboysPKCowboys
New Orleans SaintsSt. Louis RamsNO -5.5Saints
Arizona CardinalsTennessee TitansARI -3Cardinals
Cincinnati BengalsPittsburgh SteelersCIN -3Bengals
Baltimore RavensDetroit LionsDET -6Ravens
Spreads provided by Vegas Insider

JACKSONVILLE, FL - SEPTEMBER 29:   Maurice Jones-Drew #32 of the Jacksonville Jaguars watches the action during the game against the Indianapolis Colts at EverBank Field on September 29, 2013 in Jacksonville, Florida.  (Photo by Sam Greenwood/Getty Images
Sam Greenwood/Getty Images

Jacksonville Jaguars (+2 vs. Buffalo Bills)

The Jaguars have won four out of their last five after starting the season off 0-8. While NFL fans might not be paying attention to this team anymore, it is actually playing pretty well as of late.

The Bills rushing defense is putrid. Jacksonville's Maurice Jones-Drew has put up three straight weeks of over 75 yards and posted a 100-yard rushing game last week. This is a matchup made in heaven for Jacksonville.

While the Bills are very capable of beating any opponent by stopping the pass and getting their own running game going, they just got shut down by a Tampa Bay Buccaneers team that is very similar to the Jaguars and lost by 21 points.

Prediction: Jaguars 24, Bills 13

PITTSBURGH, PA - SEPTEMBER 22:  Jay Cutler #6 of the Chicago Bears drops back to pass during warm ups before the game against the Pittsburgh Steelers on September 22, 2013 at Heinz Field in Pittsburgh, Pennsylvania.  (Photo by Justin K. Aller/Getty Images
Justin K. Aller/Getty Images

Chicago Bears (+2 at Cleveland Browns)

The Bears have been absolutely awful on defense, but their offense has been good enough to win games. While they've gone 3-2 over their last five games, the Bears will have Jay Cutler back behind center against a top-10 passing defense.

If Matt Forte can get the offense started against a Browns defense that only allows 98 yards per game—ranking fourth in the NFL—and take some of the weight off Cutler's shoulders, expect the Bears to roll. But much of this prediction is dependent on one of the two facets of this Chicago offense getting going.

The Browns proved last week that they can contend with any team as they came within two minutes of defeating a very good New England Patriots team. But returning home to face a Chicago team that is finally fully healthy is not exactly a good matchup for this team.

Prediction: Bears 27, Browns 21

PITTSBURGH, PA - DECEMBER 08:  Charles Clay #42 of the Miami Dolphins celebrates after scoring on a 12 yards touchdown pass against the Pittsburgh Steelers during the game on December 8, 2013 at Heinz Field in Pittsburgh, Pennsylvania.  (Photo by Justin K
Justin K. Aller/Getty Images

Miami Dolphins (+2.5 vs. New England Patriots)

Here's the biggest upset prediction of the weekend. The Patriots are a top-five team in the NFL, but with the loss of Rob Gronkowski for the season, the makeup of this team will have to change once again against a tough Miami Dolphins team on the road.

Aside from the loss of Gronkowski, it appears Aaron Dobson, another starting receiver for the Patriots, is still missing practice after being inactive in Week 14, according to Mike Reiss of ESPN:

Ryan Tannehill has been playing very well as of late for the Dolphins. Miami has gone 3-1 in its last four games thanks to Tannehill averaging over 277 yards per game along with seven touchdowns. The only issue for the second-year starter will be cutting down on the four interceptions he's thrown over that stretch.

FOXBORO, MA - DECEMBER 08:  Rob Gronkowski #87 of the New England Patriots catches a pass before being hit by T.J. Ward #43 and D'Qwell Jackson #52 of the Cleveland Browns  in the third quarter during the game at Gillette Stadium on December 8, 2013 in Fo
Jared Wickerham/Getty Images

Tannehill will be facing off with Tom Brady, who has certainly proven that he can get the job done with just about any group around him. In just seven starts on the season, though, Gronkowski caught 39 passes on 67 targets from Brady for 592 yards and four touchdowns.

The Patriots have lost the physicality and size of Gronkowski and will have to replace it with young receivers like Kenbrell Thompkins and slot receivers like Julian Edelman and Danny Amendola. That won't be enough against Miami.

Prediction: Dolphins 28, Patriots 24