On Wednesday December 4, however, the Scot will welcome his former team to the Theatre of Dreams for the very first time, keen to extend United's unbeaten run to 13.
His successor at Goodison Park, Roberto Martinez, has hit the ground running since taking charge and has been performing minor miracles on Merseyside with Everton currently fifth yet arguably in direct competition with Arsenal for the honour of producing the most attractive football in the league.
By comparison, United sit in eighth and have struggled to string together a consistent thread of convincing performances, especially when transitioning between the league and Europe, where Moyes' team have so far enjoyed their most emphatic displays this season.
Wayne Rooney and co. head into their home showdown with the Toffees following a 2-2 draw away to Tottenham Hotspur which itself was preceded by a stunning 5-0 demolition of Bayer Leverkusen in Germany.
Meanwhile, Everton head to Manchester in red hot form having smashed Stoke City 4-0 at the weekend.
Can Moyes launch the home side up the table by making a statement against his old club?
Much will come down, as ever, to his team selection, so why not hit the button below to start up the slideshow preview on how United could line-up against Everton.