The St. Louis defense was able to create solid pressure and the unit held strong in the red zone, limiting the 49ers to field goals for the most part. But lack of production on offense killed the Rams.
Throw in numerous dropped passes and a bundle of killer penalties early on, and it's not hard to figure out how the Rams let this game get out of hand.
The Rams will have a shot at redemption next week against the tough Arizona Cardinals, while the 49ers will attempt to maintain their Wild Card lead over Arizona when they host the division-leading Seahawks next Sunday.
For now, here are my takeaways from St. Louis' loss to San Francisco.