The attacking partnership of Luis Suarez and Daniel Sturridge has been a revelation thus far in the 2013/14 campaign, moving above and beyond the fruitful first six months that emerged between the two in the latter half of last season.
Playfully dubbed Liverpool's "SAS," Sturridge and Suarez stand out as the Premier League's most in-form strike pairing, having scored a remarkable 18 goals between them.
However, the duo will suffer disruption this weekend after the news emerged that the English half of the relationship was likely to be missing for the trip to Hull City, as was confirmed by FIFA:
Sturridge's ankle injury means that Suarez will either welcome a new rotation of partners on Sunday or, as he has done so many times prior to last January, roam the Reds' attacking line on his own.
The simple fact being that whatever option Brendan Rodgers decides to take, the Uruguayan international is sure to cope.
Despite languishing in the bottom half of the table as things stand, one particular statistic that Steve Bruce's Tigers will take great pride in is the fact that his side currently have the best home defence in the English top flight, conceding an average of just 0.33 goals per game at home.
What those numbers don't tell you, however, is that Hull are yet to truly be tested at the KC Stadium this term; none of the teams who have made the trip thus far are currently in the top half of the table, with 12th-ranked Aston Villa being the highest-placed club to have done so.
Bruce's central defensive options are the ones most likely to provide opposition to Suarez this weekend, but the likes of Curtis Davies, Abdoulaye Faye and Alex Bruce all have a certain tinge of Championship quality about them.
Up against Phil Jagielka and Sylvain Distin last weekend, arguably one of the best centre-back partnerships in the league, the South American showed that his input can be felt even against the best.
Granted, his stunning 30-yard free-kick wasn't as a result of any fine poaching to suggest that he took advantage of that defence, but his hounding presence was an essential part in the Reds claiming a 3-3 draw from the Merseyside derby.
With Sturridge out, it's likely that Rodgers will pack his midfield and see the likes of Philippe Coutinho and Jordan Henderson offer the most support up top, but by no means would those two be deemed as "striking partners."
It's a tactic that Liverpool became familiar with at the start of the season as Suarez's 10-match suspension ran its course, except this time it will be Sturridge sitting out.
Not to heap misery on Crystal Palace, but anything the Premier League new boys can do, having won 1-0 at Hull last weekend, Liverpool have shown they're certainly capable of doing better.
Liverpool are entering a favourable run of fixtures and couldn't have hoped for a much better time for one of their star forwards to pick up a knock, with Suarez ready to deputise with flying colours in his absence.