The San Diego Chargers marched into Arrowhead Stadium and pulled off the upset on a last-minute touchdown by Seyi Ajirotutu to stun the Chiefs, 41-38.
Philip Rivers threw for 392 yards and three touchdowns, including the game-winner to Ajirotutu on a 26-yard throw to the corner of the end zone with 31 seconds remaining in the game. Danny Woodhead had a receiving touchdown and a rushing touchdown while Keenan Allen hauled in nine catches for 124 yards.
Alex Smith finished with 294 yards passing and three touchdowns, but the Chiefs QB threw a late interception that was converted into points. Jamaal Charles rushed for 115 yards and two touchdowns, while Donnie Avery added 91 yards receiving and a score.
Trailing 14-3 after Charles' first rushing touchdown in the second quarter, Rivers hit Woodhead for an 11-yard score with 22 seconds remaining before halftime. What was initially a defensive struggle in the first half turned into a shootout in the third quarter as both teams combined for 28 points.
After Dwayne Bowe's five-yard grab in the fourth quarter gave Kansas City a four-point lead with 1:28 remaining in the game, San Diego drove 78 yards in seven plays to set up Ajirotutu's game-winning touchdown catch. The Chargers snapped their three-game losing streak with the win while the Chiefs have now lost two straight after starting the season 9-0.