No. 20 Oklahoma @ Kansas State, 12 p.m. ET, Fox Sports 1
Kansas State did the unthinkable last season by going into Norman and upsetting the Sooners 24-19. Now Oklahoma could be on upset alert again.
Freshman Trevor Knight is expected to start while Blake Bell recovers from a concussion.
The offense will also be without running back Damien Williams and wide receiver Lacoltan Bester, who have been suspended for Saturday’s game.
Bill Snyder's Wildcats are on a four game winning streak heading into Saturday, and have the talent to make it five. The Wildcat offense has averaged 39.5 points its past four wins, and the defense, led by Ty Zimmerman, has played well against the run this season.
Kansas State has only given up 137.0 rushing yards per game this season, and it's something that could cause significant problems for Knight, who relies on his legs to make plays.
The Wildcats will get their first win at home against the Sooners since 1996.
Prediction: Kansas State 31, Oklahoma 27
Michigan @ Iowa, 12 p.m. ET, Big Ten Network
Brady Hoke's Wolverines barely got out of Evanston with a win, as they needed a 44-yard field goal as time expired to knot things up at 9-9 and three overtimes to escape with a 27-19 victory. While Michigan may have pulled off their seventh win of the season, it has not scored more than one touchdown in regulation since its win against Indiana on Oct. 19.
The offense, led by quarterback Devin Gardner, has clearly struggled, and it could be another tough game for it.
Iowa has exceeded expectations this season and will challenge the Wolverines up front on defense. The Hawkeyes defense is averaging only 130.0 rushing yards per game. Don't count out Iowa's offense, though, as running back Mark Weisman is physical and can make plays on the ground.
It will be a low-scoring game that will be decided late in the fourth quarter. Look for big plays from Wolverine wide receivers Jeremy Gallon and Devin Funchess down the stretch, along with key field goals from placekicker Brendan Gibbons.
Brady Hoke's squad will escape Kinnick Stadium with tough road win.
Prediction: Michigan 23, Iowa 20
No. 13 Michigan State @ Northwestern, 12 p.m. ET, ESPN
A win for Michigan State guarantees it a spot in the Big Ten Championship, but will Northwestern finally get a win it has been hoping to get since Sept. 21?
The Spartan defense continues to be the best in the country by only surrendering 228.0 yards per game. The offense continues to improve with Connor Cook under center, Jeremy Langford racking up yards on the ground and the receiving corps continuing to make big plays in key situations.
Northwestern has fallen off the grid after once being a Big Ten Big Legends Division title contender. Pat Fitzgerald's team has been unluckiest team this season with six consecutive losses, including two overtime losses and a last-second Hail Mary touchdown.
Northwestern will give Michigan State trouble, but it fall once again in the fourth quarter.
Prediction: Michigan State 34, Northwestern 26
No. 5 Oregon @ Arizona, 3:30 p.m. ET, ABC/ESPN2
Oregon should be more determined than ever after bouncing back with a 44-21 win over Utah last week. A Stanford loss at USC last week also gives the Ducks a chance to win their next two games and host the Pac-12 Championship game on Dec. 7.
While the Oregon offense, led by quarterback Marcus Mariota, has struggled to score points in the first half recently, it takes over in the second half and blows its opposition away.
Arizona has lost its past two games, which were at home, by a combined 12 total points. Last week, it was a surprising loss to Washington State, who it had not lost to since 2004.
The Wildcats defense is going to have trouble containing the Ducks' high-octane offense, meaning it will be Arizona's sixth straight loss to Oregon.
Prediction: Oregon 45, Arizona 24
Boise State @ San Diego State, 10:30 p.m. ET, CBS Sports Network
It's a big game for Boise State, who is looking to win its last two games to reach the first annual Mountain West Conference Championship game and hopefully get another shot at knocking off potential BCS buster, Fresno State.
Since Joe Southwick suffered a broke ankle, Grant Hedrick has stepped in and played big role in the success of the Broncos offense. The running game has been solid with Jay Ajayi (1,078 yards, 15 TDs) as well.
San Diego State was a last-second field goal away from taking the driver's seat in the West Division, but Fresno State blocked it and won in overtime 35-28 on Oct. 26.
The loser of this matchup is eliminated from winning its division title. The Aztecs have proved to surprise opponents this season, but the Broncos will come away with the win.
Prediction: Boise State 37, San Diego State 28