Both clubs have started the season in impressive fashion, with the Toffees in sixth place and their neighbours three points better off in second.
Despite finishing above their rivals for the past two seasons, Everton endured a dismal derby record under David Moyes. In 11 years, Moyes oversaw just three Premier League wins in 22 games against Liverpool, taking a paltry 16 points from a possible 66.
The fact Martinez boasts a better record while at Wigan will encourage fans, with the Catalan claiming two wins and three draws in eight meetings with the Reds.
Here's a look at where Everton must improve to mark Martinez's first derby with a win.