Stanford continues to pile up the profits as a road team, going 14-3 against the spread in 17 recent games away from home. And they look to extend a 6-1 ATS run at USC, when they visit the Trojans Saturday in Pac 12 action.
Point spread: USC opened as three-point home underdogs; the total was 46 Wednesday. (Line updates and matchup report)
Odds Shark computer says: 35-32 Stanford
Why Stanford can cover the spread
The Cardinal have averaged 36 points per game over their last half-dozen meetings with the Trojans, winning five of those six contests. Stanford comes to play when it's Southern Cal on the other sideline.
Stanford boasts a profitable 14-3 ATS run in its past 17 road games and 6-1 ATS in seven visits to USC.
Why Southern Cal can cover the spread
Southern Cal would like nothing better than to put a massive dent in Stanford's BCS chances by knocking off their longtime rival at Homecoming this week. The Trojans, now bowl eligible, will also be keen on ending a four-game skid vs. the Cardinal.
They will be motivated as a small home underdog in a conference battle.
Stanford is your play here, as it has won the last four games and five of the last six. Last season's result alone should give the team confidence with how well it dominated, as the Cardinal outgained the Trojans 417 to 280 in total yards and held USC to 26 yards on the ground.
Stanford is 14-3 ATS in its last 17 games on the road
Stanford is 6-1 ATS in its last seven games at Southern Cal