Week 11 features many favorable matchups, and Arizona Cardinals receiver Larry Fitzgerald is one star who is sure to have a big game this weekend.
The players on this list aren't going to be the No. 1 players at their positions. Those are no-brainers, although Minnesota Vikings running back Adrian Peterson will be challenged in Seattle. These players all have the potential to put up huge numbers, but they haven't been fantasy stars every week in 2013.
Based on their talent and their opponent, the stars on this list are primed for big games this weekend.
Here's a list of players who are sure to make a splash along with fantasy projections, with points per ESPN standard scoring.
Robert Griffin III, QB, Washington Redskins
It's desperation time for Washington. It will travel to Philadelphia to take on the Eagles. Philadelphia is tied atop the NFC East at 5-5, and Washington is tied for last at 3-6. If Washington is going to have any chance of making a magical run for a second straight season, Robert Griffin III will have to carry the team.
Although fantasy owners don't care about wins and losses, a desperate quarterback can pay off.
In Week 1 against the Eagles, Griffin threw for 329 yards with two touchdowns and two interceptions.
He has usually put up strong numbers against the Eagles. In three games, he has averaged 242.3 passing yards. The second-year quarterback has also thrown for nine touchdowns to four interceptions in those games.
Fantasy owners are beginning to see Griffin heat up. He has thrown for at least 280 yards in three of the last four games. The 23-year-old has six touchdowns during that stretch.
Griffin is also starting to run the ball more. He has at least five carries in five straight games and topped 40 rushing yards three times in that span.
Philadelphia ranks 31st against the pass and 14th against the run. It ranks 20th in scoring defense by allowing 24.4 points per game. All signs point to Griffin having a big game against the Eagles.
Fantasy projection: 290 passing yards, 2 TD, 1 INT; 6 carries, 35 rushing yards (20 points)
Jamaal Charles, RB, Kansas City Chiefs
Jamaal Charles ranks fifth in the NFL with 725 rushing yards, but he hasn't been a huge factor in fantasy leagues recently. Although he always puts up consistent numbers, this will be a big week for him.
Fantasy owners have seen the running back's point total decline steadily since Week 6. He went through a similar three-game stretch near the beginning of the season, so look for him to put up scoring numbers this week.
The Chiefs will head to Denver to take on the Broncos in a huge showdown. Charles will be getting a lot of carries early in the game to try to set the tone. If Kansas City's defense can contain Peyton Manning, Charles will be a big factor throughout the game.
He ran for 160 yards on 37 carries in two meetings last season. Now that the Chiefs are in a rhythm, Charles will be fed the ball more this time around.
Denver ranks fourth against the run. That doesn't look very good for Charles, but the Broncos get up on teams early and force them to throw the ball. Washington's Alfred Morris ran for 93 yards and a score on 17 carries against Denver three weeks ago.
Kansas City has a defense that can slow down Denver's offense, which will allow Charles to get his touches.
Fantasy projection: 26 carries, 113 yards, 1 TD (17 points)
Larry Fitzgerald, WR, Arizona Cardinals
Although he hasn't put up many fantasy points in recent weeks, Larry Fitzgerald is due for a big game this week.
The veteran receiver has only nine receptions for 98 yards and a score in the last three games. Quarterback Carson Palmer has been finding other receivers, but he will be able to find his No. 1 target.
Arizona will take on the Jacksonville Jaguars, which is a favorable matchup. The Jaguars have allowed 18 passing touchdowns, which is tied for 26th. Like Denver, Jacksonville's defensive numbers are a bit skewed. Teams have gotten out to big leads against the Jaguars, so they have turned to running the football. That helps explain why they are ranked 32nd against the run.
Jacksonville allows 32.3 points per game, which ranks 32nd, and Fitzgerald leads the Cardinals with five touchdowns. The 6'3" receiver will be Palmer's main target near the end zone, so be sure that he is in your lineup.
Over the last seven games, Fitzgerald has had a touchdown in every other game. That trend will continue as he will find the end zone this week.
Fantasy projection: 6 receptions, 85 yards, 1 TD (14 points)
*All stats are courtesy of NFL.com