1. LeSean McCoy, Philadelphia Eagles: Shady McCoy exploded back on the scene last week against the Green Bay Packers. Racking up 155 yards rushing on 25 carries, McCoy's elite vision and burst was on display throughout the game. Now facing a Washington Redskins defense that has given up 31.9 points per game will allow McCoy to do his thing once again.
2. Jamaal Charles, Kansas City Chiefs: With a prime-time showdown against the Denver Broncos on the horizon, the Chiefs are going to give Jamaal Charles lots of touches. Look for him to become the focal point once again of this Kansas City offense.
3. Marshawn Lynch, Seattle Seahawks: Averaging 6.0 yards per carry over his last two games, Marshawn Lynch now gets the honor of playing a Vikings team that just gave up 139 yards to Washington Redskins running back Alfred Morris. Can you say beast mode?
4. Alfred Morris, Washington Redskins: Don't look now, but Alfred Morris is third in rushing yards this season. With back-to-back 100-yard performances under his belt, Morris should be able to continue his strong 2013 fantasy campaign against an Eagles defense that is allowing 110.5 rushing yards per game.
5. Frank Gore, San Francisco 49ers: With 700 yards and seven rushing touchdowns on the season, Frank Gore is doing what he does best—producing at a steady level for the San Francisco 49ers. With an offensive philosophy that's centered on running the football, Gore will always have plenty of opportunities to find pay dirt.
6. Adrian Peterson, Minnesota Vikings: Lost amongst all of the Vikings struggles this season has been the stellar play of their iconic leader Adrian Peterson. With 786 yards rushing and nine touchdowns to his credit, AP has shown the world he is the most talented running back in the game today.
7. Reggie Bush, Detroit Lions: Part of the division-leading 6-3 Detroit Lions, running back Reggie Bush has been a huge part of this team's success. With 966 total yards of offense, Bush will get plenty of touches once again this week against the Pittsburgh Steelers.
8. Eddie Lacy, Green Bay Packers: With quarterback Aaron Rodgers out with a broken collarbone, the Packers have shifted their offense around rookie running back sensation Eddie Lacy. A bone-rattling runner, Lacy is a handful to bring down. This week against the New York Giants, expect more of the same hard-nosed running from from the former Alabama standout.
9. Ray Rice, Baltimore Ravens: It's been a shocking fall from grace for Ray Rice. Usually one of the most productive players in all of fantasy football, Rice has accumulated just 289 yards rushing this season on 115 carries. If there's any chance for Rice to break out, Week 11 against the Bears is it. Allowing a whopping 129.4 rushing yards a game, there will be no excuse this week if he doesn't get his act together.
10. Matt Forte, Chicago Bears: Chicago Bears head coach Marc Trestman has really turned this offense into an exciting one to watch. With a dual-threat running back like Matt Forte at his disposal, Trestman has given his star back 201 touches so far this season. Forte should get back to work and put up points this week against a Ravens defense that is giving up 342.2 total yards per game this season.
11. Knowshon Moreno, Denver Broncos: Playing on a ridiculously good offense, Broncos running back Knowshon Moreno has blossomed into a fantasy star this season. With nine total touchdowns to his credit, no matter what defense he goes up against, Moreno always has a chance to score. That trend will continue in Week 11 vs. the Kansas City Chiefs.
12. Le'Veon Bell, Pittsburgh Steelers: In six games this season, Steelers running back Le'Veon Bell has compiled 339 yards rushing and four touchdowns. While he hasn't performed like fellow rookie backs Giovani Bernard or Eddie Lacy, Bell's style of rushing fits this offense perfectly. Taking on the Detroit Lions in Week 11, watch for Bell to get the lion's share of work once again.
13. Andre Brown, New York Giants: In his triumphant return to the New York Giants, running back Andre Brown rushed for 117 yards and a touchdown on 30 carries. Forget being eased back into things, Brown is back and ready to perform for this struggling Giants offense.
14. Ben Tate, Houston Texans: With ESPN's Adam Schefter reporting that Texans running back Arian Foster will miss the remainder of the season because of a bulging disc in his back, backup running back Ben Tate has stepped into the primary role. This week, though, you may have to temper your expectations for Tate going up against the Oakland Raiders' sixth-ranked run defense.
15. Lamar Miller, Miami Dolphins: Arguably the most frustrating running back in fantasy football this season has been Miami Dolphins speedster Lamar Miller. Although he's had a few solid performances this season, Miller has yet to register 20 carries in a single game. Play him with caution this week against the San Diego Chargers.
16. DeAngelo Williams, Carolina Panthers: Competing with both Mike Tolbert and Jonathan Stewart for carries, DeAngelo Williams will look to put up gaudy numbers against a weak New England Patriots run defense. Even though the matchup looks great on paper, Williams' limited workload is terribly concerning for fantasy owners.
17. Chris Johnson, Tennessee Titans: For fantasy owners this season, Chris Johnson has been frustrating to watch. Coming off a big game against the St. Louis Rams in Week 9, Johnson struggled to get anything going last week against the Jacksonville Jaguars. Now facing a Colts defense that has been vulnerable against the run, Johnson will have a shot to do big things once again in Week 11.
18. Stevan Ridley, New England Patriots: If you stuck with Stevan Ridley this season, congratulations. Ridley has bounced back from a horrible start, scoring double-digit fantasy points in four straight games. This week, though, Ridley will be challenged. Facing the Carolina Panthers' second-ranked run defense won't be an easy task for any New England running back.
19. Andre Ellington, Arizona Cardinals: With each passing week, Arizona Cardinals rookie running back Andre Ellington is showing the world he has a bright future in this league. A speedy runner with great vision, it feels like Ellington is always one touch away from ripping off a big chunk of yardage.
20. Danny Woodhead, San Diego Chargers: While he hasn't rushed for more than 36 yards in a single game this season, San Diego Chargers running back Danny Woodhead has become a versatile weapon for this offense. Catching 53 passes for 408 yards and four touchdowns, Woodhead has more receptions than Dallas Cowboys wide receiver Dez Bryant.