Last year, Stanford halted Oregon 17-14 in Eugene, ending the Ducks' run to the national title.
UO is again on a crash course for the national title game and will have to go through Stanford.
This time around, the Ducks will be out to prove that loss was a fluke. Jon Wilner of the San Jose Mercury News outlined the stakes of this upcoming contest and called this the biggest game ever played on The Farm:
Oregon dropped to No. 3 this week in the BCS standings, but a difficult schedule should catapult the Ducks into the national title game -- if they run the table.
Stanford also is in contention. Despite a loss at Utah three weeks ago, the Cardinal (No. 5 in the BCS) controls its own destiny in the Rose Bowl race and remains in the hunt for a berth in the title game. It must win out and get a little help.
Measured by the participants' position in the BCS standings and The Associated Press rankings, this is the biggest game ever played at Stanford Stadium.
For those who have written off the Ducks based on last year's results, take a quick look back. UO averaged 50 points per game in its last three trips to Stanford and 47.4 points in its five dates with the Cardinal before last season.
Stanford will also have to face a tougher Duck defense than last season and a more experienced quarterback, Marcus Mariota. It will face that test without a key member of its defense, defensive end Ben Gardner, who was lost for the season.
Tune in to ESPN at 9 p.m. ET Thursday to see if the Cardinal can bounce the Ducks from the national title picture once again.