Roma continue to march on, but the Bianconeri are hanging in there and remain just five points behind the Giallorossi.
Antonio Conte's slight rotation was not costly, as Paul Pogba, Andrea Barzagli and Kwadwo Asamoah sat on the bench.
Some solid performances from Martin Caceres, Mauricio Isla and Paolo De Ceglie helped to keep squad members sharp against the Elefanti.
More changes could be instilled by Conte with an eye on the Champions League encounter against Real Madrid next week.
Leonardo Bonucci could swap places with Barzagli and take a rest ahead of the mouthwatering clash with Los Merengues at the Juventus Stadium.
The ball-playing centre-back hit the headlines midweek as Italian newspaper Gazzetta dello Sport reported that the player was caught speeding in his Ferrari by police, but it appeared as if there were no ramifications at Juve, as Bonucci kept his place on Wednesday.
Bonucci could be kept fresh for Cristiano Ronaldo et al. next week, with Angelo Ogbonna stepping into the line-up.
In the engine room, Conte continues to swap and change among his four masterful centre-midfielders and Andrea Pirlo's game time appears to have begun to be managed more carefully.
The regista could pave the way for Pogba to step back into the side as Conte continues to search for the best possible combination from his wealth of options.
The wide areas also have plenty of competition for places, and the Chilean Isla could earn another start as he gradually settles into life at Juve after his debut season was marred by injuries.
Asamoah could reclaim a place, though, with De Ceglie not doing enough to hold off the Ghanaian on the left of midfield.
The competition for places is great to see, but with their place in the knock-out phase of the Champions League in jeopardy, that extra depth might not be needed when the final months of the season come around.
Fernando Llorente has been good, if not spectacular, while Fabio Quagliarella and Mirko Vucinic have been injured—both of whom could stake claims to start ahead of the Spaniard when fit.
The former Athletic star is under fierce competition from Sebastian Giovinco, with Formica Atomica offering more fluidity and athleticism next to Carlos Tevez.
Further rotation could be risky with the gap at the top already five points and Napoli level on points with them, too, but their precarious position in Europe has forced the coach's hand.
Gianluigi Buffon; Andre Barzagli, Angelo Ogbonna, Giorgio Chiellini; Mauricio Isla, Paul Pogba, Arturo Vidal, Claudio Marchisio, Kwadwo Asamoah; Sebastian Giovinco, Carlos Tevez.