South Carolina comes into this game riding high off last week's 27-24 two-overtime victory at previously unbeaten and No. 5-ranked Missouri.
Avoiding a letdown will be paramount for a Gamecocks team that have played their way back into the SEC East chase.
Things set up favorably for the Gamecocks, who have an off week next week before closing out the conference portion of their schedule at home against Florida.
In fact, the Gamecocks are finished with the road. Remaining games against Coastal Carolina and Clemson also are at home, where South Carolina has won 14 straight.
Mississippi State has won its last two, but it has been a struggle.
The Bulldogs beat Bowling Green 21-20 and Kentucky 28-22 with both victories at home. Mississippi State's only other victories were against Alcorn State and Troy.
Who: No. 14 South Carolina Gamecocks (6-2, 4-2 SEC) vs. Mississippi State (4-3, 1-2 SEC)
When: 12:21 p.m.
Where: Williams-Brice Stadium, Columbia, S.C.
Watch: SEC TV
Series history: South Carolina leads 8-6
Unless otherwise noted, all rankings refer to BCS.