No. 4 Ohio State has won 20 consecutive games and is coming off a 63-14 rout of the Penn State Nittany Lions.
This Saturday, the Buckeyes (8-0) will travel to West Lafayette, Ind., to face Purdue (1-6), the team that came the closest to ruining Ohio State's perfect run.
Last year, the Boilermakers invaded Columbus, Ohio, knocked Braxton Miller out of the game and dominated in the trenches on their way to a 22-14 fourth-quarter lead.
That set the stage for Kenny Guiton and the Buckeyes to orchestrate one of the most improbable comebacks of the year.
The backup quarterback drove 75 yards with less than a minute to go and connected with Chris Fields from two yards out for a touchdown. Guiton tied the game on the ensuing two-point conversion with a pass to Jeff Heuerman, and Ohio State dominated in overtime to secure a 29-22 victory.
The Boilermakers have struggled lately, but they've had surprising success against Ohio State—especially at home, where they've won three of the last four against the Buckeyes.
Will Purdue's luck continue this year? According to Vegas Insider, it isn't likely as Ohio State is favored by 31 points.
Get all the details of Saturday's matchup with this complete game preview.
Date: Saturday, Nov. 2
Time: 12 p.m. ET
Place: Ross-Ade Stadium; West Lafayette, Ind.
TV: Big Ten Network