The Spurs did not look good defensively or on the boards, and just about the only part of their team in midseason form was Gregg Popovich, who trolled Craig Sager as only Pop can do.
San Antonio shot 35-of-88 in the game, just 40 percent, despite shooting a very respectable 7-of-18 from three-point range.
San Antonio elected to sit Kawhi Leonard and Manu Ginobili against Houston, using a big and unconventional starting lineup of Tony Parker, Danny Green, Boris Diaw, Tim Duncan and Tiago Splitter.
James Harden gashed the Spurs' defense for 22 points and 11 assists in just under 30 minutes of work, and a hot shooting third quarter from Houston ultimately proved to be the difference in the contest.
Facing a significant deficit, Popovich pulled his starters during the third quarter and the game turned into a battle of the benches for much of the second half.
The Spurs ended their preseason at 3-4, but don't worry, Popovich likely will not lose much sleep over it as San Antonio prepares for its season opener at home against the Memphis Grizzlies.