Belgium confirmed their automatic qualification to Brazil 2014 with a 2-0 win over Croatia last Friday in Group A, a day which also saw Wales beat Macedonia, 1-0, at home.
Chris Coleman's side may be heading to Brussels with little to play for besides pride and form heading into the impending Euro 2016 qualifiers, but with their hosts likely to be sapped of their intensity through their success, Wales may not have to try too hard to go out of the World Cup qualifiers with a bang.
That's not to say that Belgium will drop points at home, but a less determined defence may let slip a consolation goal or two.
After all, Kompany and Co. have only dropped one point in their nine qualifying games so far.
Should Scotland and Macedonia enjoy better luck elsewhere, Wales could drop to the bottom of the table to become the wooden spoon winners of Group A.
Venue: King Baudouin Stadium, Brussels
Date: Tuesday Oct. 15
Time: 8 p.m. BST
Live Stream and TV Info
TV: Sky Sports 3, 5:55 p.m. BST
Sam Vokes returns to the Wales squad after having overcome an ankle injury, as Craig Bellamy and Chris Gunter are set to win their 78th and 50th caps, respectively.
Meanwhile, Marouane Fellaini is ruled out for Belgium due to suspension and a wrist injury.
At this stage, Belgium won't be keen to drop unnecessary points, regardless of their opposition, and Wales will face a real struggle to get anything from their game in Brussels.
Regardless of who they play up front, the home side are overflowing with flair, attacking talent and well-rounded defenders. It would be a surprise if they didn't take all three points through a commanding lead against Coleman's visitors.
As reported by the BBC, Coleman is unsure about his future as Wales boss and this game could turn out to be his match for signing off as national manager.
With a number of exciting young players in their ranks, ranging from Gareth Bale and Aaron Ramsey to Jonathan Williams, a change of coach may be in order to assert a grander vision for the future, perhaps with Belgium as a model of excellence of sorts.
Returning to the game at hand, however, it seems as though the upstarts from the low countries will finish on a triumphant high.
Final: Belgium 4, Wales 1