A disappointing draw in the previous match has put Portugal in desperate position in World Cup qualifying, but you can be certain this group will fight until the end. This could end up being bad for Luxembourg in the upcoming battle.
After Friday's 1-1 result against Israel, Portugal stand three points away from Russia for the Group F title. Considering there is only one match remaining and they trail by seven in goal differential, winning the group seems incredibly unlikely.
However, the squad is assured a second-place spot and a place in the final playoff, so it would like to have some momentum going forward.
On the other side, Luxembourg will be trying simply to avoid last place, which has been a competitive battle including Northern Ireland and Azerbaijan. Still, the squad does have three draws and a win in nine matches, which makes it quite dangerous.
Both sides will be fighting hard for a victory in this match, so make sure not to miss a second of the action.
Who will win?
When: Tuesday, Oct. 15 at 1 p.m. ET, 6 p.m. BST
Where: Estadio Cidade de Coimbra, Coimbra, Portugal
Watch: ESPN Deportes
Live Stream: ESPN3
Odds (via Paddy Power): Portugal (1-50), Luxembourg (40-1), Draw (16-1)
Top Storyline: Can Portugal Win Without Cristiano Ronaldo?
At the end of Portugal's match against Israel, Cristiano Ronaldo picked up a late yellow card that caused him to be suspended for the upcoming battle against Luxembourg.
Some even debated whether this was on purpose to go into the playoffs with a clean slate, including analysts at ESPN:
Regardless of why he is not playing, the point is that he will not be there for the upcoming match. This could cause the home team to struggle without one of the best players in the world.
As a result, guys like Hugo Almeida, Helder Postiga and Nani must step up on the attack to make up for Ronaldo's absence. If they cannot handle the pressure, Portugal could be in serious trouble.
Prediction: Portugal 3, Luxembourg 0
Even without Ronaldo on the pitch, Portugal should have more than enough to handle the overmatched opponent. There are experienced offensive players who have the ability to create opportunities for themselves, even with increased attention.
However, the question will be whether the defense can hold strong. The late goal allowed against Israel was not a fluke but rather another example of poor mistakes by the back line.
Portugal will try to get their first clean sheet in five matches while ending this round of qualifying on a high note against Luxembourg.
Follow Rob Goldberg on Twitter for the latest breaking news and analysis.