Several unknown players turned out to be fantasy heroes for lucky owners in Week 5, including rookies like Geno Smith and Terrance Williams.
But one breakout performance doesn't guarantee anything for the next week.
Below, I'll highlight fringe players set to take the field in Week 6 and offer fantasy advice for each.
*Standard league scoring stats according to ESPN Fantasy.
Brandon Weeden, Cleveland Browns, QB
Brian Hoyer's season-ending knee injury opens the door for Brandon Weeden in Week 6. But standing in his way is the Detroit Lions defense.
While the Lions only rank 20th in fewest passing yards allowed this season, they rank seventh in the league in fewest touchdown passes allowed through five games, giving up just five to this point.
Bleacher Report's Josh Zerkle considers Weeden a must-add for fantasy owners in need of a quarterback this fall, but I have to disagree, at least in Week 6.
Just look at how well Detroit's secondary fared against Aaron Rodgers in Week 5. The Lions held the former MVP to just 274 yards and one touchdown. More than 80 of those yards came on a long touchdown pass to James Jones, the only really big play Rodgers had all game long.
Fantasy Play: Sit
Danny Woodhead, San Diego Chargers, RB
San Diego Chargers playmaker Danny Woodhead came back down to earth in Week 5's loss to the Oakland Raiders, but look for him to bounce back against the Indianapolis Colts on Monday Night Football this week.
Woodhead should find yards easier to come by on the ground against Indy's 30th-ranked rush defense. Meanwhile, the Colts' top-10 pass defense downfield should open up additional opportunities for Woodhead out of the backfield as a receiver.
He caught a season-high nine passes in Week 5 and is Philip Rivers' second favorite target behind Antonio Gates.
Fantasy Play: Start
Terrance Williams, Dallas Cowboys, WR
The Washington Redskins' pass defense might not be quite as dreadful as the Denver Broncos', but it's pretty close. And that's great news for Terrance Williams owners this weekend.
The Cowboys' rookie wideout caught a career-high seven passes in Week 4 and exploded in Week 5 to the tune of 151 yards and a touchdown on just four catches. Don't expect the former Baylor star to average 38 yards per catch again in Week 6, but you can anticipate another successful outing against the league's 28th-ranked pass defense.
What's more, Williams is a big-play threat who doesn't need a ton of receptions to make a mighty impact for your squad this weekend. And it certainly doesn't hurt that he's available in most leagues across the country.
Fantasy Play: Start
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