Matchups are everything in fantasy football, and there are some tight ends, kickers and defenses with the potential to fall victim in Week 5.
That makes scouring the waiver wire a must, as is the case each week. There are always some gems to be found if you look hard enough, and checking out whom each target is playing is also very important.
Let's take a look at some must-sit starters for the less marquee—but still important—positions in fantasy football with a possible replacement for each.
Sit: Vernon Davis, San Francisco 49ers
If you own Davis this season, you know his last two games have been total wash-outs, with the star tight end compiling just five catches for 38 yards and one touchdown. He's also missed one game in between due to injury.
The Niners' passing attack (No. 27 in NFL) as a whole has been largely ineffective this season, as Colin Kaepernick has been nothing short of disappointing, with 856 yards passing to the tune of five touchdowns and four interceptions with a 58.1 percent completion rate through four games.
Adding to the concerns about starting Davis in San Fran's lackluster passing game, their Week 5 opponent, the Houston Texans, are ranked No. 1 in the league against the pass and have allowed just 15 total points to tight ends in fantasy leagues, good for third-fewest among defenses.
Waiver-Wire Replacement: Dallas Clark, Baltimore Ravens
Availability: Owned in 5.8 percent of ESPN leagues.
Clark isn't an explosive option by any means, but he is serviceable nonetheless. The Ravens tight end is second on the team in targets (29), receptions (16) and yards (175) this season, so he'll see some action. Clark will also be up against the Miami Dolphins defense, which has allowed a fantasy-leading 16.3 points per week against opposing tight ends.
Sit: Dan Bailey, Dallas Cowboys
Whether you're thinking of keeping him as your starter or picking him up off the waiver wire, don't start Dan Bailey this week. He's missed two field goals in his last two games and won't have many chances to correct his problems against a tough Denver Broncos defense.
Denver has been good enough to support its high-powered offense this season. Despite a No. 30-ranked pass defense, the Broncos have halted opponents on the ground to the tune of the No. 1 rush defense in football and recently shut down the Philadelphia Eagles potent offense with just 20 points allowed in Week 4.
Waiver-Wire Replacement: Greg Zuerlein, St. Louis Rams
Availability: Owned in 24 percent of ESPN leagues.
Zuerlein will get plenty of chances at extra points and field goals, as the lowly Jacksonville Jaguars have allowed the third-most points in the NFL this season. The Rams kicker has shown his range in the past after booting a 60-yard field goal last season, and he's 6-for-6 in attempts this year. St. Louis' struggles offensively of late will ensure it falls just short on some drives and sets up a big day for the kicker.
Sit: Cincinnati Bengals
The Bengals are normally a solid starter each and every week of the season, but Week 5 presents a stiff challenge as they take on the New England Patriots.
New England has a revived ground game that ranks No. 11 in the NFL, and despite a No. 17 ranking in the passing attack, future Hall of Fame quarterback Tom Brady and company are getting better and better as the season progresses.
The Pats may be getting some reinforcements for this game against the Bengals, as receiver Danny Amendola (questionable, groin) has a good chance to play, per ESPN.com. Meanwhile, tight end Rob Gronkowski looks more like an outside shot, as he hasn't ruled out a return in Week 5 but looks more likely to return in Week 6, per Jay Glazer of FOX Sports.
Still, the Pats offense is coming off a week in which it compiled 448 total yards against the Atlanta Falcons, and weapons like Julian Edelman and Kenbrell Thompkins are picking up the slack while Brady's top targets are gone.
Waiver-Wire Replacement: Cleveland Browns D/ST
Availability: Owned in 4.9 percent of ESPN leagues.
After allowing just six points to the Bengals last week, the Browns continue to prove their defense is legit, and their eighth-best mark of 17.5 points per game allowed furthers that sentiment.
In Week 5, the Browns will be up against a rookie quarterback in EJ Manuel and the Buffalo Bills. The Bills are horrid in the air with the No. 28 passing attack, but their ground game is ranked No. 2. Don't worry about that, though, because the Browns are No. 4 against the run and will be stacking the box in anticipation of Buffalo's rushing attack.