Well, I guess fans in Manchester can all take solace in the fact that their most bitter rival lost, too.
That's because for the first time since September 13, 2008, both United and City were held to zero points in an EPL match on the same day.
For a little perspective, the last time both United and City lost an EPL match on the same day, Shia LaBeouf was still relevant, capturing our hearts with such classics as "Indiana Jones and the Kingdom of the Crystal Skull" and "Eagle Eye."
The last time both United and City lost an EPL match on the same day was during the season in which Nicholas Anelka led the league in goals and Liverpool finished second on the table.
So, yeah, Saturday was a somewhat odd day in the Premier League.
Let's take a closer look at what went wrong for the Manchester clubs.
Aston Villa 3, Manchester City 2
A season removed from a 15th-place finish and near relegation, Aston Villa is putting together a very strong campaign. The Claret and Blue have now beaten Champions League sides Arsenal and Manchester City and sit in ninth place with nine points in six matches.
While the win over the Gunners came when Arsenal was most vulnerable, Saturday's defeat of City was a gritty, remarkable effort that truly showed this team's resolve.
Playing without Christian Benteke and Gabriel Agbonlahor, Paul Lambert's side twice fell behind at Villa Park but never gave in.
After Yaya Toure's strike put The Citizens in front 1-0 heading into the locker room, Karim El Ahmadi came out and equalized in the 51st minute following a beautiful piece of individual play and pass from Leandro Bacuna.
Edin Dzeko responded five minutes later to put City ahead, 2-1, but Villa once again responded, this time with a perfectly placed free kick from Bacuna that left Joe Hart helpless:
Two minutes later, Andreas Weimann capitalized on calamitous defending from Matija Nastastic, Vincent Kompany and Hart to punch in the game-winner, sending Villa Park into an absolute frenzy.
City looked up to the task on the attack, controlling 67 percent of the possession, completing 88 percent of their passes and firing off 21 total shots. Toure and Samir Nasri were especially impressive.
But in the end, atrocious defending from City, a dogged, implacable effort from Villa and some magic from the 22-year-old Bacuna in just his fourth EPL appearance were the difference.
Manchester United 1, West Bromwich Albion 2
The panic level at Old Trafford has reached a new high, and even that's a bit of an understatement.
Morgan Amalfitano got the scoring started for West Brom in the 54th minute when he made Rio Ferdinand look like a statue with a transcendent piece of individual play and chip over David De Gea.
Wayne Rooney, who was one of the few Red Devils who looked ready to play on Saturday, equalized moments later on a free kick.
West Brom came right back, however, as Saido Berahino put The Baggies ahead in the 67th minute after more weak defending from the side in red. Steve Clarke's side then defended well and held on with relative ease in front of a quiet Old Trafford crowd.
ESPN's Twitter feed summed up the rare result and United's now historically bad EPL start:
The Red Devils are 2-1-3 and sit in 13th place, tied with Stoke City and Newcastle with seven points.
Unsurprisingly following Saturday's flat effort, "#MoyesOut" was trending on Twitter.
It's hard to completely blame Moyes, but you have to think United under Sir Alex Ferguson would have found a way to at least equalize in the final 20 minutes with Robin van Persie coming on as a sub.
Give West Brom credit. They now have eight points in six matches. But this was a very un-Manchester-United-like performance, especially at home.
Note: All stats courtesy of WhoScored.com