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Clay Matthews is the heart and soul of Green Bay's defense, so losing him for any amount of time could be costly for the Packers.
UPDATE: by Jesse Reed at 3:10 p.m. ET on Monday, Sept. 23
After leaving the game against the Cincinnati Bengals with a hamstring injury, Matthews told reporters that he was sat for precautionary reasons and that he didn't foresee missing any time, as noted by Weston Hodkiewicz of the Green Bay Press-Gazette:
I’ll be good. I think today was more of a preventive measure than anything. I felt like I could go back out there, but we have to be smart, especially going into a bye week. I don’t see myself missing any time. We have Detroit coming back and I’ll be out there.
The Packers have a bye in Week 4, so as long as his injury isn't too severe, there's a good chance Matthews will be ready to roll for the team's next contest.
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Matthews left the team's game against the Cincinnati Bengals after suffering a hamstring injury, as noted by the Packers, and he was questionable to return:
Matthews has been an absolute terror off the edge for the Packers this year, and he'll be missed if he can't play in Week 5.