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Liverpool’s unbeaten record came to an end as Southampton produced a brilliant display to secure a 1-0 win at Anfield.
The Reds lost Philippe Coutinho to injury earlier in the week, and they lacked his creative spark for much of the contest.
Southampton stunned Anfield when taking the lead on 53 minutes. Dejan Lovren showed tremendous strength to shake off his marker and power a header on goal from a corner. Steven Gerrard attempted to keep the ball out, but he could only divert it into the roof of the net.
Saints could have doubled their lead moments later, but Simon Mignolet produced a superb save to keep out Osvaldo’s drive.
With no Coutinho and Luis Suarez, Gerrard is the focal point for Liverpool, and he went close to a leveller, but Artur Boruc kept out his free kick.
Southampton should have put the game safe, but Mignolet showed exactly why Reds boss Brendan Rodgers brought him to the club in the summer with a brilliant triple save to deny the visitors a second goal.
Raheem Sterling had a late chance to snatch a point, but his touch let him down when in on goal.
Match Stats (Four Four Two)
Shots: Liverpool 10-12 Southampton
Corners: Liverpool 6-6 Southampton
Possession percentage: Liverpool 55.3-44.7 Southampton
Passes Completed:Liverpool 360-268 Southampton
Fouls Committed:Liverpool 6-9 Southampton