According to the Chicago Tribune's Brad Biggs, Marshall left Thursday's practice with a bothered back.
Fantasy owners should remain patient before freaking out, especially as long as the team conveys an optimistic outlook on their top target. But should he be unavailable for their Sunday night showdown against the Pittsburgh Steelers, Alshon Jeffery becomes an awfully intriguing option.
Last season, Jay Cutler threw 194 of his 434 pass attempts (44.7 percent) Marshall's way. Only Calvin Johnson received more targets. Cutler has struggled to build a rapport with any other receiver, but Marshall's absence would force the issue.
Jeffery is beginning to receive some more responsibility during his second season. Last week, the 23-year-old was targeted eight times, catching five of them for 42 yards. After seeing only 48 passes go his direction last season, that's a promising sign.
Marc Trestman is trying to spread the football around, but the depth chart is severely shallow after Marshall and Jeffery. If Marshall can't play or is even limited, Jeffery could easily get double-digit targets.
While Pittsburgh's passing defense ranks ninth in the NFL with 397 total passing yards allowed through two contests, the stats are padded due to facing the run-heavy Tennessee Titans during Week 1. Andy Dalton held his own against the Steelers Monday night, compiling 280 passing yards.
Jeffery is only worth playing in deeper leagues with a healthy Marshall, but those who own him in 12-team leagues might want to utilize him if Marshall cannot suit up.