Well, it was the Seattle Seahawks, if it somehow slipped your mind. In their last two games against the Seahawks, the 49ers have been outscored 71-16.
Simply put, the 49ers have yet to figure out this Seahawks team led by Pete Carroll and company. Week 2 was a disaster, and the quicker they forget about that game, the better.
Moving on, the 49ers face the Indianapolis Colts at home. The Colts, like the 49ers, have a 1-1 record, and will look to put a disappointing loss in the rear view mirror as they head to Candlestick Park.
The Colts are formidable, led by young quarterback Andrew Luck; however, the 49ers should find this opponent far easier than their divisional rivals.
Here are four reasons why the 49ers will bounce back in Week 3.
The Seahawks aren't the only great home team.
In a little more than two seasons, the San Francisco 49ers have complied a 13-2-1 record at Candlestick Park.
With regards to the Indianapolis Colts, their road record is anything but impressive. In their lone season with Andrew Luck at the helm, the Colts went 4-4 on the road in 2012.
In that same time span, the Colts were outscored 164-71 in their four road losses. The largest defeat came at the hands of the New England Patriots, 59-24.
This could be a rough game for the Colts.
The 49ers ground game has looked awful to start the regular season. In the first two games, the 49ers have rushed for only 190 yards on the ground.
Last season, the 49ers were the second-best rushing attack behind Robert Griffin III and the Washington Redskins. It's still early in the season, but the 49ers currently have the 17th best rushing attack, tied with the Cincinnati Bengals.
I expect this stat to improve as the season progresses, only because this 49ers team boasts a top-shelf offensive line. Don't forget the stable of talented running backs at the 49ers' disposal, including Pro Bowl back Frank Gore.
The Indianapolis Colts also have a very shaky defense. Against the run, the Colts have given up 272 rushing yards and three touchdowns on the ground. Not to mention, the Colts allowed 4.5 yards per carry to opposing teams in the first two games.
Look for a bounce-back performance from the young quarterback.
The 49ers' ground game should improve, but also look for Kaepernick to slice up this Colts secondary. Statistically speaking, the Colts have a shot at defending Kaepernick; however, stats don't show the whole picture.
The Colts are 16th against the pass in the first two weeks, but this is still a secondary that has yet to play away from Lucas Oil Stadium. If you just look at last season, the Colts secondary was pretty awful, especially on the road.
If Vernon Davis can suit up this Sunday, the Colts will have their hands full defending both Davis and Anquan Boldin.
Looking at the film from the most recent 49ers-Seahawks game, you could point to a whole host of issues that would jump out on tape. The 49ers' pass rush would be one of those issues.
Aldon Smith was solid off the edge, but everyone else was average to subpar. The 49ers did a solid job in getting after Russell Wilson, but the run defense was atrocious.
Despite his reputation, Justin Smith was held in check for most of the game. Ray McDonald and Ahmad Brooks were solid, but the Seahawks exploited the duo at times.
Glenn Dorsey was also subpar in the game, though he did receive his first sack as a 49er.
Simply put, this unit has to be more consistent. Luckily for the 49ers, they face a subpar Colts offensive line. Aldon Smith and Justin Smith should have huge games against Colts left tackle Anthony Castonzo.
We could see the 49ers pile up on the sacks in Week 3.