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Studs: Bernard Pierce, Doug Martin, Marshawn Lynch
Bernard Pierce will look to step up with Ray Rice's injury. Even if Rice plays, one has to think that he'll be limited. Pierce is a really talented back and has the potential to be a monster if given a bigger workload.
Martin has essentially carried the Tampa Bay offense so far this season, showing the tremendous combination of speed and power that made him one of the league's best backs as a rookie last year. Look for him to be relied on against New England and have another big game.
Lynch is in full "beast mode" right now, and he's the focal point of Seattle's offense. He'll get a ton of touches against Jacksonville, which has one of the weakest defenses in the league, giving up an average of 173.5 yards on the ground the first two games.
Duds: LeSean McCoy, Daryl Richardson, C.J. Spiller
Kansas City has one of the best rush defenses in the league, and Andy Reid knows how to stop McCoy. With two weeks of film now on Chip Kelly's offense, it will be interesting to see what adjustments are made to slow down McCoy and the Eagles.
Richardson has not gotten much going in the rushing game, and Isaiah Pead returned from his suspension last week and predictably did not get much work. But if Richardson is ineffective again this Sunday, Pead could very well take over and eliminate Richardson's value.
Spiller has not sprinted out of the gates like many expected, and although he hasn't been bad by any stretch, Fred Jackson's success has to be a little concerning. The Bills are also going up against the Jets' underrated run defense.