The Southeastern Conference has four teams—Alabama, Texas A&M, LSU and Georgia—rooted in the BCS championship conversation, as the league looks to win its eighth straight national title.
Oregon and Stanford of the Pac-12 Conference have other plans, as the two West Coast programs are looking to take the next step and end the SEC's reign.
Meanwhile, Ohio State is looking to do the same under head coach Urban Meyer, who started the SEC's streak while at Florida in 2006.
Finally, Clemson and Florida State have entered their names in the running under thanks to tremendous quarterback play from Tajh Boyd and Jameis Winston.
Do any of these programs have the gusto to take the title, or will the SEC reign supreme once again?
Note: Rankings based on the Week 2 USA Today Coaches Poll.
Georgia played its way back into the BCS championship conversation with a Week 2 win over South Carolina.
Even with the key victory, a lot will still have to fall in the Bulldogs' favor for them to reach the title game.
UGA must win out and win the SEC title over an undefeated and, preferably top-ranked, Alabama or Texas A&M squad.
This could very well happen, as the Bulldogs are as talented as any team in college football.
Essentially, if only one of the current non-SEC contenders—Oregon, Ohio State, Stanford and Clemson—ends the season undefeated and the Dawgs win out, they are likely headed for the BCS title game.
In the end, the Bulldogs are strong enough to beat any team in the country, while chances are also good that multiple teams in front of them fall.
Florida State looked great in its season opening win over Pittsburgh. Much of that was thanks to the exceptional play of redshirt freshman quarterback Jameis Winston.
FSU's BCS chances hinge on an Oct. 19 date with No. 4 Clemson on the road in Death Valley.
That will be Winston's first game in truly hostile territory against an elite senior quarterback in Tajh Boyd.
With that said, the Tigers remain the outright favorite to win the Atlantic Coast Conference, until the Seminoles can prove otherwise.
LSU has looked as strong as any team in the country thus far.
However, the Tigers will face one of the most formidable schedules in college football on their road to the BCS.
The Tigers will travel to Georgia, Mississippi State, Ole Miss and Alabama, and they will also host Florida, Texas A&M and Arkansas.
If they make it through all of that, they will still have to win the SEC title game to earn a BCS title shot.
While the Tigers are looking very good, especially thanks to quarterback Zach Mettenberger's hot start, they just aren't talented enough to make it through that murderous schedule unscathed.
It will be a monumental failure if Louisville doesn't finish the regular season undefeated.
UL doesn't have a single ranked team on its 2013 slate, but even if the Cardinals make it through the rest of their cakewalk schedule without a loss, they will likely be left out of the BCS title game.
An undefeated SEC, Pac-12, ACC or Big Ten team will take precedence over UL. Additionally, a one-loss SEC team would almost certainly have a better resume than Louisville.
To make it to the title game, the Cards will need to be the luckiest group in college football and see nearly every top team in college football drop in front of them.
With a win over Alabama, Texas A&M will be in the drivers seat to make the BCS title game.
However, even if the Aggies fall to the Crimson Tide, they could still end up in Pasadena.
Alabama laid out that blueprint in 2011-12, when it lost to LSU during the regular season, only to earn a BCS title game rematch with the undefeated Tigers.
A&M will need some help to do so this season, if they lose to the Crimson Tide.
Even despite the vast number of contenders, as Oregon, Kansas State, Alabama and others proved last season, it is very difficult to go undefeated.
Texas A&M may not have a typical SEC defense, but the Aggies might have the most talented offense in the nation, which is enough to give them a serious chance.
Clemson is in control of its own destiny in the ACC and stands as the favorite to win the conference.
The Tigers could still need some help if they win out, however.
The Tigers are currently at No. 5 and, if an SEC team stays undefeated along with either Oregon, Stanford or Ohio State, Clemson might be on the outside looking in.
At the same time, the likelihood of so many teams remaining undefeated is small.
All Clemson can really do is focus on going 13-0 and winning the ACC title, which it has the talent to do, particularly with stars Tajh Boyd and Sammy Watkins.
Stanford blindsided Oregon in a 17-14 overtime upset in Eugene last season.
Again this year, all roads point to that game carrying enormous BCS title implications.
This time, though, the Cardinal will have to not only beat Oregon to make the title game, but they'll have to do what they couldn't last year: win all their other games.
Stanford lost twice last season to Notre Dame and Washington.
This season, they'll have to take down Oregon, Notre Dame, Washington and a red-hot UCLA team.
While the Stanford defense will keep every game close, the Cardinal offense won't be strong enough to carry them through a season full of close calls.
The Big Ten Conference has looked very strong in the early going.
Wisconsin, Michigan, Northwestern and Nebraska all look capable of competing for the league title.
However, Ohio State still remains the overwhelming conference favorite when at full strength.
The Buckeyes haven't shown too much in their first two wins, but there is no doubt the talent is there on both sides of the ball.
Much like Clemson, OSU remains the favorite in its conference until proven otherwise.
Oregon has looked the part of a national title contender more so than any team in the nation so far.
The Ducks currently rank No. 2 in total offense and No. 7 in scoring defense, as they have outscored their foes 125-13.
UO boasts two of the most electric players in the country at their positions in quarterback Marcus Mariota and all-purpose back De'Anthony Thomas.
As they have looked unbeatable in the first two weeks, the Ducks look poised to exact revenge on Stanford and take their second shot at the BCS title game.
If they win out, there is no doubt they are in.
Will this be the year Oregon takes the final step up and grabs the crystal football?
Alabama's situation is identical to that of Texas A&M.
A win over the Aggies in College Station will keep the Crimson Tide in control of their destiny.
A loss could still end up in the Tide taking the back door into the title game like they did in 2012.
While Alabama didn't look great in Week 1 against Virginia Tech, there is no questioning this team's talent.
Alabama has an experienced quarterback, bruising running backs, talent on the outside and a nasty, punishing defense. If the Tide offensive line comes together, UA will be looking like the unbeatable giant that won the last two national titles.
Plenty of teams are vying to knock Alabama off, but Nick Saban and Company just might not let that happen.