South Carolina has beaten Georgia in three consecutive football seasons, but only has one SEC East title to show for it, with the Bulldogs winning the last two.
The Gamecocks are hoping a victory over the Bulldogs this year will be a springboard to the SEC Championship Game.
Georgia, meanwhile, is trying to avoid starting the season at 0-2.
The Bulldogs will be without the services of wide receiver Malcolm Mitchell, who suffered a season-ending knee injury in Georgia's 38-35 loss at Clemson last week.
South Carolina emerged from last Thursday's 27-10 victory over North Carolina relatively injury-free. The one injury of note was starting center Cody Waldrop's sprained ankle.
If Waldrop is unable to go, the Gamecocks will play redshirt freshman Clayton Stadnik.
Who: South Carolina (1-0, 0-0 SEC) at Georgia (0-1, 0-0 SEC)
When: 4:30 p.m., ET
Where: Sanford Stadium, Athens, Ga.
Series history: Georgia leads, 43-17-2
Unless otherwise noted all quotes obtained firsthand.