While most punters might have Leicester down as firm favorites to repeat their success of last season, Saracens' summer activity in the transfer market gives them an edge.
Mark McCall's side were overpowered by the Northampton front-row in last season's semi-final and have take steps to prevent that happening again by signing giant prop James Johnston from Harlequins.
Johnston was the cornerstone of the Quins pack last season and adds some vital ballast to the North London club alongside Lions prop Mako Vunipola.
Mako Vunipola is joined by his younger brother Billy at No. 8, and together with Johnston these three have the potential to steamroll most Premiership packs.
Johnston will provide stability and the Vunipola brothers a wrecking-ball edge in the loose.
Look out also for fly-half Owen Farrell to make great strides this season. Farrell's abilities have looked limited at times, but he grew in stature during the British and Irish Lions tour this summer and looks set to take his game to a new level.
Saracens finished top of the table in the Premiership's regular season, and we can expect them to go one better this time round and add to the title they won in 2010/11.