Internazionale start their Serie A campaign Sunday, hosting Genoa at the Stadio Giuseppe Meazza.
The Nerazzurri have undergone substantial change over the summer—most significantly changing managers from the inexperienced Andrea Stramaccioni to the mastermind behind Napoli's recent rise: Walter Mazzarri.
A change in policy has seen a host of younger, less heralded players arrive at Appiano, with Mazzarri tasked with blooding a new generation of stars at Inter capable of replicating the success that Jose Mourinho achieved in recent times.
A comfortable win at home to Cittadella in the Coppa Italia last weekend was a gentle beginning to the season, but the league is where it will really count this season, and Moratti will be quietly hopeful that Inter can be a surprise candidate for a place in the top three.
Genoa arrive in Milan with plenty of changes themselves—as usual under Enrico Preziosi—with Fabio Liverani the latest Mister to take the reigns at the Marassi.
Plenty of new faces have arrived, most notably Francesco Lodi, who starred for Catania last year and will be the side's regista, pulling the strings from deep.
When: Sunday, Aug. 25 at noon ET (5 p.m. BST)
Where: Stadio Giuseppe Meazza, San Siro, Milan, Italy
Live stream: BT Sport, Bet 365
TV: BT Sport, beIN Sport
One to watch for the hosts: Fredy Guarin
One of the keys to Mazzarri's Napoli side was the ability to spring devastating counterattacks with a strong, dynamic centre-midfield.
Fredy Guarin fits this bill and will have license to contribute at both ends of the pitch, which should really suit his game, neither burdening him with being the sole ball-winner or the only creative influence in the final third.
Esteban Cambiasso and Ricky Alvarez will be able to ensure a smooth transition for the Nerazzurri from defence to attack, and Guarin will be tasked with knitting it all together.
When sides used to sit deep against the Partenopei, the option of Blerim Dzemaili or Gokhan Inler firing in long-range shots was always an asset, which is another asset that the Colombian will bring to Mazzarri's system.
One to watch for the visitors: Mario Santana
Liverani will look to field a Christmas tree formation with the Grifone, with three centre-midfielders and two attacking midfielders.
The Rossoblu will have a solid base for the attacking midfielders to link with Alberto Gilardino—who'll remain with Genoa for the time being after returning from his loan at Bologna—and Liverani will have a host of options to play in behind the striker.
Alongside Mario Santana, there will be Moussa Konate and Andrea Bertolacci competing for a place in the starting lineup, but it will be the Argentine—who shone for Torino last term—who will be the main fixture in this advanced role.
Giampiero Ventura managed to get him ticking again, but injuries prevented Santana from really demonstrating what he is capable of, so a move to Genoa presents the challenge of proving himself all over again.
Sime Vrsaljko arrives from Dinamo Zagreb this summer, where his form has earned him several caps for the Croatian national team, despite being just 21 years old.
The Croat will make his debut at the weekend and will have a tough task at right-back in Liverani's system due to the lack of cover in the advanced areas down the right flank.
Alvaro Pereira should be handed a start, although Yuto Nagatomo could easily switch to the left, making room for the Brazilian Jonathan to feature on the right.
Mazzarri will probably opt for the Uruguayan though, and this will be a great chance for the 27-year-old to reignite a rather flat career with the Nerazzurri since his move from Porto last year.
If he can provide good service for Rodrigo Palacio and Mauro Icardi from deep, it should entice his young opponent to press him higher up the pitch, and this will open up the possibility of ghosting around the outside, as he did to such good effect during his days with the Dragoes.
On the other hand though, should Vrsaljko be able to avoid any nerves on his debut and shut down any Nerazzurri threat from the left, one would expect Inter to become frustrated.
Luca Antonelli is one of the finest left-backs in the league, and should he deal with Nagatomo on the opposite flank, the game might become very congested with six midfielders in the central areas from both sides.