It's impossible to predict the best plays of college football's Week 1—or, for that matter, of any week. Part of what makes a pick-six so thrilling is its unpredictability; if you were able to forecast its occurrence, it wouldn't be nearly as fun to watch.
But while there's no way to guess at the physical "highlights" you'll see replayed on Sunday, Sept. 1, it is possible to guess at some of the highlighted stat lines.
Who will throw for 500 yards and take an early lead in the race for the Davey O'Brien Award, given to the nation's best quarterback? Who will rush for 200 yards and three touchdowns? Even if the numbers come against inferior competition, who will make a statement toward becoming a Heisman dark horse?
By looking at which blue-chip players take on no-chip defenses, a grainy picture of the post-Week 1 world comes to light. It isn't clear enough to make any confident assertions, but what's the harm in trying?