1.) Adrian Peterson, Minnesota Vikings: History hasn't been kind to 2,000-yard rushers or the last five top fantasy backs, but Peterson thrives on being the exception to the rule. He's not the slam dunk top pick that many think, but it'd be hard to pass on his upside at 1.01.
2.) Doug Martin, Tampa Bay Buccaneers: Martin's fantasy production last year was inflated by two huge games, but the fact remains that he's a talented runner and receiver who is the unquestioned lead back for his team.
3.) Arian Foster, Houston Texans: Foster's career-low 4.1 yards a carry in 2012, 350+ carries last year and a healthy Ben Tate are all concerns, but Foster has averaged 53 receptions and over 15 total touchdowns a year over the last three seasons.
4.) Jamaal Charles, Kansas City Chiefs: Peterson's miraculous recovery from an ACL tear hogged the headlines, but Charles topped 1,500 rushing yards in his own rebound season last year. The West Coast offense of Andy Reid made fantasy studs of Brian Westbrook and LeSean McCoy, and Charles has the skills to excel in the scheme as well.
5.) C.J. Spiller, Buffalo Bills: If you're the type who likes risk/reward picks, then Spiller is your man. A capable receiver who averaged six yards a carry in 2012, Spiller could be set for a huge season if he gets 300+ touches in 2013.
6.) Ray Rice, Baltimore Ravens: The middle of a fantasy draft is generally considered an unfavorable slot, but fantasy owners in 2013 can start their drafts from the middle of round one with a reliable fantasy RB1 in Rice. Believe me, you could do worse.
7.) LeSean McCoy, Philadelphia Eagles: After an injury-marred 2012 season McCoy has an excellent shot at rebounding in a big way in 2013, given how much new Philadelphia head coach Chip Kelly ran the ball at Oregon.
8.) Trent Richardson, Cleveland Browns: Rib and knee injuries limited Richardson to 3.6 yards a carry and less than 1,000 rushing yards as a rookie. However, Richardson did score 11 touchdowns on the ground in 2012 and will see a heavy workload under new offensive coordinator Norv Turner.
9.) Matt Forte, Chicago Bears: Forte isn't the flashiest first-round pick, but the sixth-year veteran has gained at least 1,400 total yards in each of his first five seasons. Forte is a solid choice as a low-end fantasy RB1 at the end of the round.
10.) Marshawn Lynch, Seattle Seahawks: Lynch topped 1,500 yards on the ground last year and gets a big boost in standard scoring formats, but his lack of involvement in the passing game limits Lynch's fantasy upside in PPR leagues.
11.) Chris Johnson, Tennessee Titans: The arrival of Shonn Greene may cost Johnson some short-yardage work, but the 27-year-old can make that ground up in the passing game and could be in for a big year behind an improved offensive line in Nashville.
12.) Steven Jackson, Atlanta Falcons: After years of posting good numbers on bad teams with the Rams, Jackson gets the best shot of his career at a deep playoff run with the Falcons. His dual-threat ability as a runner and receiver could help your fantasy squad make one as well.
13.) Alfred Morris, Washington Redskins: Morris was a revelation as a rookie in 2012, gaining over 1,600 rushing yards and finishing second in the NFL in rushing. Like Lynch, Morris isn't used much in the passing game, but he's a rock-solid pick as a fantasy RB2.
14.) Darren Sproles, New Orleans Saints: Many fantasy owners considered Sproles' 2012 season relatively disappointing, although he finished in the top 15 at his position in PPR leagues. The year before that, when Sean Payton was calling the shots, Sproles was a top-five fantasy option.
15.) Reggie Bush, Detroit Lions: After finishing as a top-15 fantasy back each of the past two years with the Miami Dolphins, Bush signed a free agent deal with the Lions. Jahvid Best was very productive when healthy as the tailback for Detroit, and there's no reason why Bush can't be as well.
16.) David Wilson, New York Giants: The release of Ahmad Bradshaw leaves Wilson as the leading candidate to be the number one back for Big Blue. The possibility of a substantial workload for Andre Brown adds some risk to drafting Wilson, but the second-year pro oozes upside.
17.) Frank Gore, San Francisco 49ers: Despite that fact that Gore finished as a top-10 fantasy back last year, the 30-year-old has been slipping in early drafts, likely due to his age. Still, the Achilles injury suffered by wideout Michael Crabtree will cause the 49ers to lean on the run even more in 2013, making Gore one of the better RB2 value picks this season.
18.) Maurice Jones-Drew, Jacksonville Jaguars: Jones-Drew led the NFL in rushing in 2011, but a Lisfranc injury wiped out most of his 2012 campaign. If he's healthy the 28-year-old has top-10 fantasy upside, but the status of his balky foot is still very much up in the air.
19.) DeMarco Murray, Dallas Cowboys: When Murray's on the field he's got game-breaking ability, but to this point in his NFL career injuries have been a big problem. Like Jones-Drew, Murray is a somewhat risky bet as your second fantasy back.
20.) Stevan Ridley, New England Patriots: The third-year pro gained over 1,250 yards on the ground for the Patriots in 2012. Given all the uncertainty surrounding the New England offense this summer, Ridley should be in for a big workload in 2013 as well.
21.) Lamar Miller, Miami Dolphins: With Reggie Bush now in the Motor City Miller moves into the lead role in the Dolphins backfield. The second-year pro doesn't have much of an NFL resume, but the talent is there for top-20 fantasy numbers if things break right.
22.) Darren McFadden, Oakland Raiders: Heading into a contract year and with a power-blocking scheme re-installed in Oakland, there's some room for optimism with McFadden. That is, until you remember that the sixth-year veteran just cannot stay healthy.
23.) Le'Veon Bell, Pittsburgh Steelers: The top rookie running back in redraft fantasy football leagues in 2013, Bell would appear to have the clearest path of all the newcomers to an every-down role, provided that he can demonstrate some ability to pick up the blitz.
24.) Chris Ivory, New York Jets: Ivory averaged over five yards a carry in limited duty over the past three seasons in New Orleans and will see the most carries of his career with the Jets. However, durability is a concern that robs some of Ivory's fantasy upside.
25.) Ryan Mathews, San Diego Chargers: Just last season some fantasy pundits were touting Mathews as a top-five pick. Now, after another injury-plagued season and with Danny Woodhead set to poach passing-down work, Mathews is a marginal fantasy RB2 at best.